4GZO

N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with hepes

Summary for 4GZO

• Entry DOI: 10.2210/pdb4gzo/pdb
• Related: 4GZP 4GZQ 4GZS 4GZT 4GZW 4GZX
• Descriptor: neuraminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total)
• Functional Keywords: beta-propella, infleunza virus, neuraminidase, hemagglutinin, hemadsorption, viral infection, sialic acid receptor, viral protein
• Biological source: Influenza A virus
• Total number of polymer chains: 1
• Total formula weight: 45021.05

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2012-09-06, release date: 2012-10-17, Last modification date: 2023-09-13)

• Primary citation: Zhu, X.,McBride, R.,Nycholat, C.M.,Yu, W.,Paulson, J.C.,Wilson, I.A.; Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.; J.Virol., 86:13371-13383, 2012; PubMed: 23015718; DOI: 10.1128/JVI.01426-12

Experimental method

X-RAY DIFFRACTION (2.6 Å)