7JN5

Crystal structure of SARS-CoV receptor binding domain in complex with human antibody CR3022

Summary for 7JN5

Entry DOI	10.2210/pdb7jn5/pdb
Descriptor	CR3022 heavy chain, CR3022 light chain, Spike glycoprotein, ... (7 entities in total)
Functional Keywords	sars, coronavirus, antibody, immune system, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	74646.52
Authors	Wu, N.C.,Yuan, M.,Zhu, X.,Wilson, I.A. (deposition date: 2020-08-03, release date: 2020-10-28, Last modification date: 2023-10-18)
Primary citation	Wu, N.C.,Yuan, M.,Bangaru, S.,Huang, D.,Zhu, X.,Lee, C.D.,Turner, H.L.,Peng, L.,Yang, L.,Burton, D.R.,Nemazee, D.,Ward, A.B.,Wilson, I.A. A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. Plos Pathog., 16:e1009089-e1009089, 2020 Cited by PubMed: 33275640 DOI: 10.1371/journal.ppat.1009089 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.705 Å)

Structure validation