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8G83
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BU of 8g83 by Molmil
Structure of NAD+ consuming protein Acinetobacter baumannii TIR domain
Descriptor: NAD(+) hydrolase AbTIR
Authors:Klontz, E.H, Wang, Y, Glendening, G, Carr, J, Tsibouris, T, Buddula, S, Nallar, S, Soares, A, Snyder, G.A.
Deposit date:2023-02-17
Release date:2023-10-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:The structure of NAD + consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
J.Biol.Chem., 299, 2023
6JD7
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BU of 6jd7 by Molmil
Crystal structure of anti-CRISPR protein AcrIIC2 dimer
Descriptor: ACETATE ION, AcrIIC2, MAGNESIUM ION
Authors:Cheng, Z, Huang, X, Sun, W, Wang, Y.L.
Deposit date:2019-01-31
Release date:2019-05-15
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
4I7F
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BU of 4i7f by Molmil
HIV-1 Reverse Transcriptase in complex with a phosphonate analog of nevirapine
Descriptor: CHLORIDE ION, MAGNESIUM ION, Reverse transcriptase, ...
Authors:Lansdon, E.B, Parrish, J.
Deposit date:2012-11-30
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Synthesis and biological evaluation of phosphonate analogues of nevirapine.
Bioorg.Med.Chem.Lett., 23, 2013
8WYP
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BU of 8wyp by Molmil
High Resolution Crystal Structure of Brd4 BD-1 in Complex with a Novel Inhibitor Precursor
Descriptor: 3-bromanylimidazo[1,2-a]pyridin-6-amine, Bromodomain-containing protein 4
Authors:Liu, B, Ma, X.
Deposit date:2023-10-31
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:High resolution crystal structure of BRD4-BD1 in complex with a novel inhibitor precursor.
Biochem.Biophys.Res.Commun., 690, 2024
6JDJ
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BU of 6jdj by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9
Descriptor: AcrIIC2, CRISPR-associated endonuclease Cas9
Authors:Cheng, Z, Huang, X, Sun, W, Wang, Y.
Deposit date:2019-02-01
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6IZO
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BU of 6izo by Molmil
Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus
Descriptor: 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER
Authors:Jiang, X, Zhang, L, Teng, M, Li, X.
Deposit date:2018-12-20
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication.
Febs J., 287, 2020
6JDX
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BU of 6jdx by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin
Descriptor: 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9
Authors:Cheng, Z, Huang, X, Sun, W, Wang, Y.
Deposit date:2019-02-02
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
4TZ4
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BU of 4tz4 by Molmil
Crystal Structure of Human Cereblon in Complex with DDB1 and Lenalidomide
Descriptor: DNA damage-binding protein 1, Protein cereblon, S-Lenalidomide, ...
Authors:Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B, Riley, M.
Deposit date:2014-07-09
Release date:2014-08-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex
To Be Published
8TXT
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BU of 8txt by Molmil
Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_W13B_B, ...
Authors:Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:2023-08-24
Release date:2024-06-26
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
8TY7
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BU of 8ty7 by Molmil
Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ...
Authors:Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:2023-08-24
Release date:2024-06-26
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
8U44
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BU of 8u44 by Molmil
CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
Descriptor: 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Moore, N, Han, J, Ward, A.B, Wilson, I.A.
Deposit date:2023-09-08
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published
8TXP
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BU of 8txp by Molmil
Crystal structure of 05.GC.w13.01 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_A, Fab heavy chain, ...
Authors:Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:2023-08-24
Release date:2024-06-26
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
8TXM
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BU of 8txm by Molmil
Crystal structure of 05.GC.w13.02 Fab in complex with H1 HA from A/California/04/2009(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_B, ...
Authors:Lin, T.H, Moore, N, Wilson, I.A.
Deposit date:2023-08-23
Release date:2024-06-26
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
Descriptor: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
Authors:Knapp, M.S, Elling, R.A.
Deposit date:2014-06-06
Release date:2014-11-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
6JE9
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BU of 6je9 by Molmil
Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers
Descriptor: AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-04
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6IFK
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BU of 6ifk by Molmil
Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound
Descriptor: CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IG0
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BU of 6ig0 by Molmil
Type III-A Csm complex, Cryo-EM structure of Csm-CTR1, ATP bound
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTR1, MAGNESIUM ION, ...
Authors:You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFY
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BU of 6ify by Molmil
Type III-A Csm complex, Cryo-EM structure of Csm-CTR1
Descriptor: CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
Authors:You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IMM
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BU of 6imm by Molmil
Cryo-EM structure of an alphavirus, Sindbis virus
Descriptor: Assembly protein E3, Octadecane, Spike glycoprotein E1, ...
Authors:Zhang, X, Ma, J, Chen, L.
Deposit date:2018-10-23
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
6IFL
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BU of 6ifl by Molmil
Cryo-EM structure of type III-A Csm-NTR complex
Descriptor: NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
Authors:You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IK4
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BU of 6ik4 by Molmil
A Novel M23 Metalloprotease Pseudoalterin from Deep-sea
Descriptor: Elastinolytic metalloprotease, GLYCEROL, ZINC ION
Authors:Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z.
Deposit date:2018-10-14
Release date:2019-10-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020
6ICW
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BU of 6icw by Molmil
Crystal structure of H7 hemagglutinin mutant AH-SGTQ (A138S, V186G, P221T and L226Q) from the influenza virus A/Anhui/1/2013 (H7N9)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Authors:Gao, G.F, Xu, Y.
Deposit date:2018-09-07
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin.
Cell Rep, 29, 2019
6ID2
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BU of 6id2 by Molmil
Crystal structure of H7 hemagglutinin mutant H7-AVTL (P221T) from the influenza virus A/Anhui/1/2013 (H7N9)
Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Authors:Gao, G.F, Xu, Y, Qi, J.X.
Deposit date:2018-09-08
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin.
Cell Rep, 29, 2019
6IF3
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BU of 6if3 by Molmil
Complex structure of Rab35 and its effector ACAP2
Descriptor: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Lin, L, Zhu, J, Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6ID5
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BU of 6id5 by Molmil
Crystal structure of H7 hemagglutinin mutant H7-SVPL ( A138S) from the influenza virus A/Anhui/1/2013 (H7N9)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Authors:Gao, G.F, Xu, Y, Qi, J.X.
Deposit date:2018-09-08
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin.
Cell Rep, 29, 2019

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数据于2024-07-24公开中

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