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8BG0
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BU of 8bg0 by Molmil
Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40
Descriptor: Amyloid-beta precursor protein
Authors:Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W.
Deposit date:2022-10-27
Release date:2023-01-18
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
8BFZ
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BU of 8bfz by Molmil
Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42
Descriptor: Amyloid-beta precursor protein
Authors:Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W.
Deposit date:2022-10-27
Release date:2023-01-18
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
3K37
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BU of 3k37 by Molmil
Crystal Structure of B/Perth Neuraminidase in complex with Peramivir
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, ...
Authors:Oakley, A.J, McKimm-Breschkin, J.L.
Deposit date:2009-10-02
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.
J.Med.Chem., 2010
3K38
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BU of 3k38 by Molmil
Crystal Structure of B/Perth Neuraminidase D197E mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
Authors:Oakley, A.J, McKimm-Breschkin, J.L.
Deposit date:2009-10-02
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.
J.Med.Chem., 2010
3K3A
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BU of 3k3a by Molmil
Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Oseltamivir
Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Oakley, A.J, McKimm-Breschkin, J.L.
Deposit date:2009-10-02
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.
J.Med.Chem., 2010
8HUB
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BU of 8hub by Molmil
AMP deaminase 2 in complex with an inhibitor
Descriptor: 3,3-dimethyl-4-(phenylmethyl)-2~{H}-quinoxaline-1-carboxamide, AMP deaminase 2, ZINC ION
Authors:Adachi, T, Doi, S.
Deposit date:2022-12-23
Release date:2023-01-18
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action.
Bioorg.Med.Chem.Lett., 80, 2023
8HU6
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BU of 8hu6 by Molmil
AMP deaminase 2 in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, AMP deaminase 2, SULFATE ION, ...
Authors:Adachi, T, Doi, S.
Deposit date:2022-12-22
Release date:2023-01-18
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action.
Bioorg.Med.Chem.Lett., 80, 2023
3AUJ
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BU of 3auj by Molmil
Structure of diol dehydratase complexed with glycerol
Descriptor: CALCIUM ION, COBALAMIN, Diol dehydrase alpha subunit, ...
Authors:Yamanishi, M, Kinoshita, K, Fukuoka, M, Shibata, T, Tobimatsu, T, Toraya, T.
Deposit date:2011-02-07
Release date:2012-02-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Redesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols
Febs J., 279, 2012
5AZV
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BU of 5azv by Molmil
Crystal structure of hPPARgamma ligand binding domain complexed with 17-oxoDHA
Descriptor: (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Egawa, D, Itoh, T, Yamamoto, K.
Deposit date:2015-10-23
Release date:2016-07-06
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
Acs Chem.Biol., 2016
5AZT
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BU of 5azt by Molmil
Ternary complex of hPPARalpha ligand binding domain, 17-oxoDHA and a SRC1 peptide
Descriptor: (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid, 15-meric peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor alpha
Authors:Egawa, D, Itoh, T, Yamamoto, K.
Deposit date:2015-10-23
Release date:2016-07-06
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
Acs Chem.Biol., 2016
3K39
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BU of 3k39 by Molmil
Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Peramivir
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, ...
Authors:Oakley, A.J, McKimm-Breschkin, J.L.
Deposit date:2009-10-02
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.
J.Med.Chem., 2010
3K36
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BU of 3k36 by Molmil
Crystal Structure of B/Perth Neuraminidase
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
Authors:Oakley, A.J, McKimm-Breschkin, J.L.
Deposit date:2009-10-02
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.
J.Med.Chem., 2010
3WDZ
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BU of 3wdz by Molmil
Crystal Structure of Keap1 in Complex with phosphorylated p62
Descriptor: Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1
Authors:Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M.
Deposit date:2013-06-26
Release date:2013-09-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Mol.Cell, 51, 2013
7E5P
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BU of 7e5p by Molmil
Aptamer enhancing peroxidase activity of myoglobin
Descriptor: DNA (5'-D(*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*AP*GP*GP*G)-3')
Authors:Tsukakoshi, K, Matsugami, A, Khunathai, K, Kanazashi, M, Yamagishi, Y, Nakama, K, Oshikawa, D, Hayashi, F, Kuno, H, Ikebukuro, K.
Deposit date:2021-02-19
Release date:2021-06-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol.
Nucleic Acids Res., 49, 2021
5Z8Y
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BU of 5z8y by Molmil
Crystal structure of human LRRTM2 in complex with Neurexin 1beta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2018-02-01
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
5Z8X
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BU of 5z8x by Molmil
Crystal structure of human LRRTM2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat transmembrane neuronal protein 2
Authors:Yamagata, A, Fukai, S.
Deposit date:2018-02-01
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
7CEG
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BU of 7ceg by Molmil
Crystal structure of the complex between mouse PTP delta and neuroligin-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3
Authors:Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
Deposit date:2020-06-23
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
7CEE
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BU of 7cee by Molmil
Crystal structure of mouse neuroligin-3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3
Authors:Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
Deposit date:2020-06-23
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.763 Å)
Cite:Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
3B2G
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BU of 3b2g by Molmil
Leptolyngbya boryana Ferredoxin
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1
Authors:Kurisu, G, Hase, T.
Deposit date:2011-08-01
Release date:2012-06-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A new structural insight into differential interaction of cyanobacterial and plant ferredoxins with nitrite reductase as revealed by NMR and X-ray crystallographic studies
J.Biochem., 151, 2012
3B2F
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BU of 3b2f by Molmil
Maize Ferredoxin 1
Descriptor: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, chloroplastic
Authors:Kurisu, G, Hase, T.
Deposit date:2011-08-01
Release date:2012-06-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A new structural insight into differential interaction of cyanobacterial and plant ferredoxins with nitrite reductase as revealed by NMR and X-ray crystallographic studies
J.Biochem., 151, 2012
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