3K39
Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Peramivir
Summary for 3K39
| Entry DOI | 10.2210/pdb3k39/pdb |
| Related | 3K36 3K37 3K38 3K3A |
| Descriptor | Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (6 entities in total) |
| Functional Keywords | influenza, neuraminidase, mutation, resistance, biocryst, peramivir, rwj-270201, bcx-1812, 229614-55-5, 229615-12-7, hydrolase, cell membrane, glycosidase, membrane, transmembrane, virion |
| Biological source | Influenza B virus (Viruses) |
| Total number of polymer chains | 16 |
| Total formula weight | 711212.52 |
| Authors | Oakley, A.J.,McKimm-Breschkin, J.L. (deposition date: 2009-10-02, release date: 2010-09-01, Last modification date: 2023-11-01) |
| Primary citation | Oakley, A.J.,Barrett, S.,Peat, T.S.,Newman, J.,Streltsov, V.A.,Waddington, L.,Saito, T.,Tashiro, M.,McKimm-Breschkin, J.L. Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses. J.Med.Chem., 2010 Cited by PubMed: 20695427DOI: 10.1021/jm100621s PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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