3K38

Crystal Structure of B/Perth Neuraminidase D197E mutant

Summary for 3K38

• Entry DOI: 10.2210/pdb3k38/pdb
• Related: 3K36 3K37 3K39 3K3A
• Descriptor: Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: influenza, neuraminidase, mutation, resistance, hydrolase, cell membrane, glycosidase, membrane, transmembrane, virion
• Biological source: Influenza B virus (Viruses)
• Cellular location: Host apical cell membrane ; Single-pass type II membrane protein : Q3S340
• Total number of polymer chains: 16
• Total formula weight: 708917.51

Authors

Oakley, A.J.,McKimm-Breschkin, J.L. (deposition date: 2009-10-02, release date: 2010-09-01, Last modification date: 2023-11-01)

• Primary citation: Oakley, A.J.,Barrett, S.,Peat, T.S.,Newman, J.,Streltsov, V.A.,Waddington, L.,Saito, T.,Tashiro, M.,McKimm-Breschkin, J.L.; Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.; J.Med.Chem., 2010; PubMed: 20695427; DOI: 10.1021/jm100621s

Experimental method

X-RAY DIFFRACTION (2.19 Å)