7QLA
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![BU of 7qla by Molmil](/molmil-images/mine/7qla) | Structure of the Rab GEF complex Mon1-Ccz1 | Descriptor: | Ccz1, Vacuolar fusion protein MON1 | Authors: | Klink, B.U, Herrmann, E, Antoni, C, Langemeyer, L, Kiontke, S, Gatsogiannis, C, Ungermann, C, Raunser, S, Kuemmel, D. | Deposit date: | 2021-12-20 | Release date: | 2022-02-09 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7QIN
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![BU of 7qin by Molmil](/molmil-images/mine/7qin) | In situ structure of actomyosin complex in skeletal sarcomere | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | Deposit date: | 2021-12-15 | Release date: | 2022-02-16 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
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7QIO
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![BU of 7qio by Molmil](/molmil-images/mine/7qio) | Homology model of myosin neck domain in skeletal sarcomere | Descriptor: | Myosin light chain 1/3, skeletal muscle isoform, Myosin regulatory light chain 2, ... | Authors: | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | Deposit date: | 2021-12-15 | Release date: | 2022-02-16 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
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7QIM
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![BU of 7qim by Molmil](/molmil-images/mine/7qim) | In situ structure of nebulin bound to actin filament in skeletal sarcomere | Descriptor: | ACTS protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wang, Z, Grange, M, Pospich, S, Wagner, T, Kho, A.L, Gautel, M, Raunser, S. | Deposit date: | 2021-12-15 | Release date: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin. Science, 375, 2022
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8RTY
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![BU of 8rty by Molmil](/molmil-images/mine/8rty) | Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.25 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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4NF9
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![BU of 4nf9 by Molmil](/molmil-images/mine/4nf9) | Structure of the Knl1/Nsl1 complex | Descriptor: | CHLORIDE ION, Kinetochore-associated protein NSL1 homolog, Protein CASC5 | Authors: | Petrovic, A, Mosalaganti, S, Keller, J, Mattiuzzo, M, Overlack, K, Wohlgemuth, S, Pasqualato, S, Raunser, S, Musacchio, A. | Deposit date: | 2013-10-31 | Release date: | 2014-03-19 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization. Mol.Cell, 53, 2014
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7NJ0
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![BU of 7nj0 by Molmil](/molmil-images/mine/7nj0) | CryoEM structure of the human Separase-Cdk1-cyclin B1-Cks1 complex | Descriptor: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1, G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin-B1, ... | Authors: | Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A. | Deposit date: | 2021-02-14 | Release date: | 2021-08-04 | Last modified: | 2021-08-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of human separase regulation by securin and CDK1-cyclin B1. Nature, 596, 2021
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7NJ1
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![BU of 7nj1 by Molmil](/molmil-images/mine/7nj1) | CryoEM structure of the human Separase-Securin complex | Descriptor: | Securin, Separin | Authors: | Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A. | Deposit date: | 2021-02-14 | Release date: | 2021-08-04 | Last modified: | 2021-08-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of human separase regulation by securin and CDK1-cyclin B1. Nature, 596, 2021
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6H3N
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![BU of 6h3n by Molmil](/molmil-images/mine/6h3n) | |
5LKI
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![BU of 5lki by Molmil](/molmil-images/mine/5lki) | Cryo-EM structure of the Tc toxin TcdA1 in its pore state | Descriptor: | TcdA1 | Authors: | Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S. | Deposit date: | 2016-07-22 | Release date: | 2016-08-31 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Membrane insertion of a Tc toxin in near-atomic detail. Nat.Struct.Mol.Biol., 23, 2016
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5LKH
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![BU of 5lkh by Molmil](/molmil-images/mine/5lkh) | Cryo-EM structure of the Tc toxin TcdA1 in its pore state (obtained by flexible fitting) | Descriptor: | TcdA1 | Authors: | Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S. | Deposit date: | 2016-07-22 | Release date: | 2016-08-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Membrane insertion of a Tc toxin in near-atomic detail. Nat.Struct.Mol.Biol., 23, 2016
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8Q4G
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![BU of 8q4g by Molmil](/molmil-images/mine/8q4g) | Thin filament from FIB milled relaxed left ventricular mouse myofibrils | Descriptor: | Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain | Authors: | Tamborrini, D, Wang, Z, Wagner, T, Tacke, S, Stabrin, M, Grange, M, Kho, A.L, Bennet, P, Rees, M, Gautel, M, Raunser, S. | Deposit date: | 2023-08-06 | Release date: | 2023-11-01 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature, 623, 2023
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8Q5H
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![BU of 8q5h by Molmil](/molmil-images/mine/8q5h) | Human KMN network (outer kinetochore) | Descriptor: | Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... | Authors: | Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S. | Deposit date: | 2023-08-09 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network To Be Published
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6XT9
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![BU of 6xt9 by Molmil](/molmil-images/mine/6xt9) | Subunits BBS 1,4,8,9,18 of the human BBSome complex | Descriptor: | BBSome-interacting protein 1, Bardet-Biedl syndrome 1 protein, Bardet-Biedl syndrome 4 protein, ... | Authors: | Klink, B.U, Raunser, S, Gatsogiannis, C. | Deposit date: | 2020-01-15 | Release date: | 2020-01-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the human BBSome core complex. Elife, 9, 2020
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6YEY
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![BU of 6yey by Molmil](/molmil-images/mine/6yey) | Xenorhabdus nematophila XptA1 in complex with porcine mucosa heparin | Descriptor: | A component of insecticidal toxin complex (Tc) | Authors: | Roderer, D, Broecker, F, Sitsel, O, Kaplonek, P, Leidreiter, F, Seeberger, P.H, Raunser, S. | Deposit date: | 2020-03-25 | Release date: | 2020-07-08 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Glycan-dependent cell adhesion mechanism of Tc toxins. Nat Commun, 11, 2020
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6YEW
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![BU of 6yew by Molmil](/molmil-images/mine/6yew) | Morganella morganii TcdA4 in complex with porcine mucosa heparin | Descriptor: | Insecticidal toxin protein | Authors: | Roderer, D, Broecker, F, Sitsel, O, Kaplonek, P, Leidreiter, F, Seeberger, P.H, Raunser, S. | Deposit date: | 2020-03-25 | Release date: | 2020-07-08 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Glycan-dependent cell adhesion mechanism of Tc toxins. Nat Commun, 11, 2020
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8RU2
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![BU of 8ru2 by Molmil](/molmil-images/mine/8ru2) | Structure of the F-actin barbed end bound by formin mDia1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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8RU0
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![BU of 8ru0 by Molmil](/molmil-images/mine/8ru0) | Structure of the undecorated barbed end of F-actin. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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8RV2
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![BU of 8rv2 by Molmil](/molmil-images/mine/8rv2) | Structure of the formin INF2 bound to the barbed end of F-actin. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-31 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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8Q6T
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![BU of 8q6t by Molmil](/molmil-images/mine/8q6t) | |
8A2Z
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![BU of 8a2z by Molmil](/molmil-images/mine/8a2z) | Cryo-EM structure of F-actin in the Ca2+-ADP nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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8A2T
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![BU of 8a2t by Molmil](/molmil-images/mine/8a2t) | Cryo-EM structure of F-actin in the Mg2+-ADP nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.24 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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8A2Y
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![BU of 8a2y by Molmil](/molmil-images/mine/8a2y) | Cryo-EM structure of F-actin in the Ca2+-ADP-Pi nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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8A2S
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![BU of 8a2s by Molmil](/molmil-images/mine/8a2s) | Cryo-EM structure of F-actin in the Mg2+-ADP-Pi nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.22 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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8A2U
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![BU of 8a2u by Molmil](/molmil-images/mine/8a2u) | Cryo-EM structure of F-actin in the Ca2+-ADP-BeF3- nucleotide state. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oosterheert, W, Klink, B.U, Belyy, A, Pospich, S, Raunser, S. | Deposit date: | 2022-06-06 | Release date: | 2022-08-10 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Structural basis of actin filament assembly and aging. Nature, 611, 2022
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