7QIM

In situ structure of nebulin bound to actin filament in skeletal sarcomere

Summary for 7QIM

• Entry DOI: 10.2210/pdb7qim/pdb
• Related: 7QIN
• EMDB information: 13990 13991 13992 13993 13998
• Descriptor: ACTS protein, nebulin (mouse), ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: skeletal muscle, sarcomere, thin filament, contractile protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 7
• Total formula weight: 228127.12

Authors

Wang, Z.,Grange, M.,Pospich, S.,Wagner, T.,Kho, A.L.,Gautel, M.,Raunser, S. (deposition date: 2021-12-15, release date: 2022-03-16)

• Primary citation: Wang, Z.,Grange, M.,Pospich, S.,Wagner, T.,Kho, A.L.,Gautel, M.,Raunser, S.; Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin.; Science, 375:eabn1934-eabn1934, 2022; PubMed: 35175800; DOI: 10.1126/science.abn1934

Experimental method

ELECTRON MICROSCOPY (4.5 Å)