Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4QXR
DownloadVisualize
BU of 4qxr by Molmil
Crystal structure of hSTING(S162A/G230I/Q266I) in complex with DMXAA
Descriptor: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION, Stimulator of interferon genes protein
Authors:Gao, P, Patel, D.J.
Deposit date:2014-07-21
Release date:2014-09-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QWN
DownloadVisualize
BU of 4qwn by Molmil
Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure
Descriptor: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2014-07-16
Release date:2014-11-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QX8
DownloadVisualize
BU of 4qx8 by Molmil
Crystal structure of histone demethylase kdm2a-h3k36me3 complex with alpha-kg
Descriptor: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
Authors:Cheng, Z.J, Patel, D.J.
Deposit date:2014-07-19
Release date:2014-11-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QEO
DownloadVisualize
BU of 4qeo by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
Descriptor: DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ...
Authors:Du, J, Li, S, Patel, D.J.
Deposit date:2014-05-17
Release date:2014-07-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4ONQ
DownloadVisualize
BU of 4onq by Molmil
Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant
Descriptor: DNA methyltransferase, SINEFUNGIN
Authors:Du, J, Patel, D.J.
Deposit date:2014-01-28
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
2RI5
DownloadVisualize
BU of 2ri5 by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with N358A point mutation
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, TRIETHYLENE GLYCOL
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-10
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RHU
DownloadVisualize
BU of 2rhu by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine and in chimera with histone H3.3(28-34)
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, N-DIMETHYL-LYSINE, ...
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RI7
DownloadVisualize
BU of 2ri7 by Molmil
Crystal structure of PHD finger-linker-bromodomain Y17E mutant from human BPTF in the H3(1-9)K4ME2 bound state
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Nucleosome-remodeling factor subunit BPTF, ...
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-10
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RI2
DownloadVisualize
BU of 2ri2 by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with D355A point mutation
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, SULFATE ION, ...
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-10
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RHI
DownloadVisualize
BU of 2rhi by Molmil
Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with H1.5K27me2 at 1.66 angstrom
Descriptor: DI(HYDROXYETHYL)ETHER, Histone H1.5, Lethal(3)malignant brain tumor-like protein, ...
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2RHY
DownloadVisualize
BU of 2rhy by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to monomethyl-lysine
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, N-METHYL-LYSINE
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2JSL
DownloadVisualize
BU of 2jsl by Molmil
Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 Natural, NMR, 10 Structures
Descriptor: HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
Deposit date:2007-07-08
Release date:2008-07-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2RHX
DownloadVisualize
BU of 2rhx by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 bound to dimethyl-lysine
Descriptor: Lethal(3)malignant brain tumor-like protein, N-DIMETHYL-LYSINE, SULFATE ION, ...
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2JSQ
DownloadVisualize
BU of 2jsq by Molmil
Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 15BrG, NMR, 10 Structures
Descriptor: HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
Deposit date:2007-07-11
Release date:2008-07-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2M0O
DownloadVisualize
BU of 2m0o by Molmil
The solution structure of human PHF1 in complex with H3K36me3
Descriptor: H3K36me3 peptide, PHD finger protein 1
Authors:Song, J, Patel, D.J.
Deposit date:2012-10-30
Release date:2013-01-16
Last modified:2013-02-27
Method:SOLUTION NMR
Cite:An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Mol.Cell, 49, 2013
2LXQ
DownloadVisualize
BU of 2lxq by Molmil
Monomeric PilE G-Quadruplex DNA from Neisseria Gonorrhoeae
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*T)-3')
Authors:Kuryavyi, V.V, Patel, D.J.
Deposit date:2012-08-30
Release date:2012-11-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5' End-Stacked Dimeric Parallel G-Quadruplexes.
Structure, 20, 2012
2RI3
DownloadVisualize
BU of 2ri3 by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with N358Q point mutation
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-10
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2LXV
DownloadVisualize
BU of 2lxv by Molmil
Dimeric pil-e g-quadruplex dna from neisseria gonorrhoeae, NMR 11 structures
Descriptor: 5'-D(*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*GP*GP
Authors:Kuryavyi, V, Patel, D.J.
Deposit date:2012-08-31
Release date:2012-11-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5' End-Stacked Dimeric Parallel G-Quadruplexes.
Structure, 20, 2012
2RHZ
DownloadVisualize
BU of 2rhz by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with D355N point mutation
Descriptor: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein
Authors:Li, H, Patel, D.J.
Deposit date:2007-10-09
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
2JMJ
DownloadVisualize
BU of 2jmj by Molmil
NMR solution structure of the PHD domain from the yeast YNG1 protein in complex with H3(1-9)K4me3 peptide
Descriptor: Histone H3, Protein YNG1, ZINC ION
Authors:Ilin, S, Taverna, S.D, Rogers, R.S, Tanny, J.C, Lavender, H, Li, H, Baker, L, Boyle, J, Blair, L.P, Chait, B.T, Patel, D.J, Aitchison, J.D, Tackett, A.J, Allis, C.D.
Deposit date:2006-11-15
Release date:2007-07-03
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs
Mol.Cell, 24, 2006
2O3M
DownloadVisualize
BU of 2o3m by Molmil
Monomeric G-DNA tetraplex from human C-kit promoter
Descriptor: 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'
Authors:Phan, A.T, Kuryavyi, V.V, Burge, S, Neidle, S, Patel, D.J.
Deposit date:2006-12-01
Release date:2007-05-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
J.Am.Chem.Soc., 129, 2007
2OE5
DownloadVisualize
BU of 2oe5 by Molmil
1.5 A X-ray crystal structure of Apramycin complex with RNA fragment GGCGUCGCUAGUACCG/GGUACUAAAAGUCGCCC containing the human ribosomal decoding A site: RNA construct with 3'-overhang
Descriptor: APRAMYCIN, MAGNESIUM ION, RNA (5'-R(*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*CP*G)-3'), ...
Authors:Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J.
Deposit date:2006-12-28
Release date:2007-02-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Apramycin recognition by the human ribosomal decoding site.
Blood Cells Mol.Dis., 38, 2007
2OE8
DownloadVisualize
BU of 2oe8 by Molmil
1.8 A X-ray crystal structure of Apramycin complex with RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang
Descriptor: APRAMYCIN, RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3')
Authors:Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J.
Deposit date:2006-12-28
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Apramycin recognition by the human ribosomal decoding site.
Blood Cells Mol.Dis., 38, 2007
2KGG
DownloadVisualize
BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
Descriptor: Histone demethylase JARID1A, ZINC ION
Authors:Song, J, Wang, Z, Patel, D.J.
Deposit date:2009-03-11
Release date:2009-05-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2H6N
DownloadVisualize
BU of 2h6n by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
Descriptor: Histone H3 K4-Me2 9-residue peptide, WD-repeat protein 5
Authors:Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006

222415

数据于2024-07-10公开中

PDB statisticsPDBj update infoContact PDBjnumon