2OE8

1.8 A X-ray crystal structure of Apramycin complex with RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang

Summary for 2OE8

• Entry DOI: 10.2210/pdb2oe8/pdb
• Related: 2OE5 2OE6
• Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3'), RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), APRAMYCIN, ... (4 entities in total)
• Functional Keywords: aminoglycoside antibiotics, apramycin, ribosomal decoding site, a site, homo sapiens, rna duplex, rna
• Total number of polymer chains: 2
• Total formula weight: 11094.97

Authors

Hermann, T.,Tereshko, V.,Skripkin, E.,Patel, D.J. (deposition date: 2006-12-28, release date: 2007-02-13, Last modification date: 2023-08-30)

• Primary citation: Hermann, T.,Tereshko, V.,Skripkin, E.,Patel, D.J.; Apramycin recognition by the human ribosomal decoding site.; Blood Cells Mol.Dis., 38:193-198, 2007; PubMed: 17258916; DOI: 10.1016/j.bcmd.2006.11.006

Experimental method

X-RAY DIFFRACTION (1.8 Å)