2RI2

Crystal structure of the 3-MBT repeats from human L3MBTL1 with D355A point mutation

Summary for 2RI2

Entry DOI	10.2210/pdb2ri2/pdb
Related	2RHI 2RHU 2RHX 2RHY 2RHZ 2RI3 2RI5
Descriptor	Lethal(3)malignant brain tumor-like protein, SULFATE ION, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	beta barrel, alternative splicing, chromatin regulator, dna-binding, metal-binding, nucleus, repressor, transcription, transcription regulation, zinc, zinc-finger
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q9Y468
Total number of polymer chains	1
Total formula weight	37248.54
Authors	Li, H.,Patel, D.J. (deposition date: 2007-10-10, release date: 2007-12-11, Last modification date: 2023-11-15)
Primary citation	Li, H.,Fischle, W.,Wang, W.,Duncan, E.M.,Liang, L.,Murakami-Ishibe, S.,Allis, C.D.,Patel, D.J. Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger. Mol.Cell, 28:677-691, 2007 Cited by PubMed: 18042461 DOI: 10.1016/j.molcel.2007.10.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation