2HDC
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![BU of 2hdc by Molmil](/molmil-images/mine/2hdc) | STRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX | Descriptor: | DNA (5'-D(P*GP*CP*TP*TP*AP*AP*AP*AP*TP*AP*AP*CP*AP*AP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*TP*TP*GP*TP*TP*AP*TP*TP*TP*TP*AP*AP*GP*C)-3'), PROTEIN (TRANSCRIPTION FACTOR) | Authors: | Jin, C, Marsden, I, Chen, X, Liao, X. | Deposit date: | 1999-05-05 | Release date: | 1999-07-05 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Dynamic DNA contacts observed in the NMR structure of winged helix protein-DNA complex. J.Mol.Biol., 289, 1999
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2E0H
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![BU of 2e0h by Molmil](/molmil-images/mine/2e0h) | |
5ESW
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![BU of 5esw by Molmil](/molmil-images/mine/5esw) | Crystal structure of Apo hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila | Descriptor: | PHOSPHATE ION, Purine/pyrimidine phosphoribosyltransferase | Authors: | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | Deposit date: | 2015-11-17 | Release date: | 2016-03-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis J.Struct.Biol., 194, 2016
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5ESX
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![BU of 5esx by Molmil](/molmil-images/mine/5esx) | Crystal structure of hypoxanthine-guanine phosphoribosyltransferase complexed with GMP from Legionella pneumophila | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Purine/pyrimidine phosphoribosyltransferase | Authors: | Zhang, N, Gong, X, Lu, M, Chen, X, Qin, X, Ge, H. | Deposit date: | 2015-11-17 | Release date: | 2016-03-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis J.Struct.Biol., 194, 2016
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7V9M
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![BU of 7v9m by Molmil](/molmil-images/mine/7v9m) | Cryo-EM structure of the GHRH-bound human GHRHR splice variant 1 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Chen, X, Yang, D.H, Wang, M.W. | Deposit date: | 2021-08-26 | Release date: | 2021-10-20 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Constitutive signal bias mediated by the human GHRHR splice variant 1. Proc.Natl.Acad.Sci.USA, 118, 2021
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4GQH
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![BU of 4gqh by Molmil](/molmil-images/mine/4gqh) | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies | Descriptor: | Capsid protein | Authors: | Li, X.Y, Song, B.A, Hu, D.Y, Chen, X, Wang, Z.C, Zeng, M.J, Yu, D.D, Chen, Z, Jin, L.H, Yang, S. | Deposit date: | 2012-08-23 | Release date: | 2013-08-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies To be Published
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7DL2
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![BU of 7dl2 by Molmil](/molmil-images/mine/7dl2) | Cryo-EM structure of human TSC complex | Descriptor: | Hamartin, Isoform 7 of Tuberin, TBC1 domain family member 7, ... | Authors: | Yang, H, Yu, Z, Chen, X, Li, J, Li, N, Cheng, J, Gao, N, Yuan, H, Ye, D, Guan, K, Xu, Y. | Deposit date: | 2020-11-25 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural insights into TSC complex assembly and GAP activity on Rheb. Nat Commun, 12, 2021
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3DWQ
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![BU of 3dwq by Molmil](/molmil-images/mine/3dwq) | Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | Descriptor: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | Deposit date: | 2008-07-22 | Release date: | 2008-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWA
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![BU of 3dwa by Molmil](/molmil-images/mine/3dwa) | Crystal structure of the B-subunit of the AB5 toxin from E. coli | Descriptor: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | Deposit date: | 2008-07-22 | Release date: | 2008-11-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.084 Å) | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWP
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![BU of 3dwp by Molmil](/molmil-images/mine/3dwp) | Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | Descriptor: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | Deposit date: | 2008-07-22 | Release date: | 2008-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3HFH
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![BU of 3hfh by Molmil](/molmil-images/mine/3hfh) | Crystal structure of tandem FF domains | Descriptor: | Transcription elongation regulator 1 | Authors: | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | Deposit date: | 2009-05-11 | Release date: | 2009-08-18 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150. J.Mol.Biol., 393, 2009
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3EU9
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![BU of 3eu9 by Molmil](/molmil-images/mine/3eu9) | The ankyrin repeat domain of Huntingtin interacting protein 14 | Descriptor: | GLYCEROL, HISTIDINE, Huntingtin-interacting protein 14, ... | Authors: | Gao, T, Collins, R.E, Horton, J.R, Zhang, R, Zhang, X, Cheng, X. | Deposit date: | 2008-10-09 | Release date: | 2009-06-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The ankyrin repeat domain of Huntingtin interacting protein 14 contains a surface aromatic cage, a potential site for methyl-lysine binding. Proteins, 76, 2009
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5GXJ
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![BU of 5gxj by Molmil](/molmil-images/mine/5gxj) | Zika Virus NS2B-NS3 protease | Descriptor: | FLAVIVIRUS_NS2B,LINKER,Peptidase S7 | Authors: | Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K. | Deposit date: | 2016-09-18 | Release date: | 2017-05-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Viral protease activation mechanism To Be Published
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3FPD
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![BU of 3fpd by Molmil](/molmil-images/mine/3fpd) | G9a-like protein lysine methyltransferase inhibition by BIX-01294 | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine, ... | Authors: | Chang, Y, Zhang, X, Horton, J.R, Cheng, X. | Deposit date: | 2009-01-05 | Release date: | 2009-02-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nat.Struct.Mol.Biol., 16, 2009
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2G3S
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![BU of 2g3s by Molmil](/molmil-images/mine/2g3s) | RNA structure containing GU base pairs | Descriptor: | 5'-R(*GP*GP*CP*GP*UP*GP*CP*C)-3', MAGNESIUM ION | Authors: | Jang, S.B, Hung, L.W, Jeong, M.S, Holbrook, E.L, Chen, X, Turner, D.H, Holbrook, S.R. | Deposit date: | 2006-02-20 | Release date: | 2007-01-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | The crystal structure at 1.5 angstroms resolution of an RNA octamer duplex containing tandem G.U basepairs Biophys.J., 90, 2006
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5H6X
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![BU of 5h6x by Molmil](/molmil-images/mine/5h6x) | The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila | Descriptor: | GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION | Authors: | Zhang, N, Chen, X, Gong, X, Ge, H. | Deposit date: | 2016-11-15 | Release date: | 2017-11-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila Crystals, 8, 2018
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2EX1
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![BU of 2ex1 by Molmil](/molmil-images/mine/2ex1) | Crystal structure of mutifunctional sialyltransferase from Pasteurella multocida with CMP bound | Descriptor: | CYTIDINE-5'-MONOPHOSPHATE, a2,3-sialyltransferase, a2,a6-sialyltransferase | Authors: | Ni, L, Sun, M, Chen, X, Fisher, A.J. | Deposit date: | 2005-11-07 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida Biochemistry, 45, 2006
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2EX0
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![BU of 2ex0 by Molmil](/molmil-images/mine/2ex0) | Crystal structure of multifunctional sialyltransferase from Pasteurella Multocida | Descriptor: | a2,3-sialyltransferase, a2,6-sialyltransferase | Authors: | Ni, L, Sun, M, Chen, X, Fisher, A.J. | Deposit date: | 2005-11-07 | Release date: | 2006-02-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida Biochemistry, 45, 2006
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4EXP
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![BU of 4exp by Molmil](/molmil-images/mine/4exp) | Structure of mouse Interleukin-34 in complex with mouse FMS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | Deposit date: | 2012-04-30 | Release date: | 2012-05-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim.Biophys.Acta, 1824, 2012
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4EXN
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![BU of 4exn by Molmil](/molmil-images/mine/4exn) | Crystal structure of mouse Interleukin-34 | Descriptor: | Interleukin-34, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | Deposit date: | 2012-04-30 | Release date: | 2012-05-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim.Biophys.Acta, 1824, 2012
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8WVB
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![BU of 8wvb by Molmil](/molmil-images/mine/8wvb) | Crystal structure of Lsd18 mutant S195M | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC | Authors: | Liu, N, Xiao, H.L, Chen, X. | Deposit date: | 2023-10-23 | Release date: | 2023-12-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
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8WVF
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![BU of 8wvf by Molmil](/molmil-images/mine/8wvf) | Crystal structure of Lsd18 mutant T189M and S195M | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC | Authors: | Liu, N, Xiao, H.L, Chen, X. | Deposit date: | 2023-10-23 | Release date: | 2023-12-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.757 Å) | Cite: | Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
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6K2H
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![BU of 6k2h by Molmil](/molmil-images/mine/6k2h) | structural characterization of mutated NreA protein in nitrate binding site from staphylococcus aureus. | Descriptor: | 1,2-ETHANEDIOL, NreA | Authors: | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | Deposit date: | 2019-05-14 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
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5IHZ
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![BU of 5ihz by Molmil](/molmil-images/mine/5ihz) | Crystal structure of anti-gliadin 1002-1E01 Fab fragment | Descriptor: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain | Authors: | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | Deposit date: | 2016-03-01 | Release date: | 2017-03-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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5IG7
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![BU of 5ig7 by Molmil](/molmil-images/mine/5ig7) | Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPQQPFP | Descriptor: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ... | Authors: | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | Deposit date: | 2016-02-27 | Release date: | 2017-03-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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