5KPC

Pavine N-methyltransferase H206A mutant in complex with S-adenosylmethionine pH 6

Summary for 5KPC

Entry DOI	10.2210/pdb5kpc/pdb
Related	5KN4 5KOC 5KOK 5KPG
Descriptor	Pavine N-methyltransferase, S-ADENOSYLMETHIONINE (3 entities in total)
Functional Keywords	benzylisoquinoline alkaloid biosynthesis, transferase
Biological source	Thalictrum flavum subsp. glaucum (Yellow meadow rue)
Total number of polymer chains	2
Total formula weight	93536.68
Authors	Torres, M.A.,Hoffarth, E.,Eugenio, L.,Savtchouk, J.,Chen, X.,Morris, J.,Facchini, P.J.,Ng, K.K.S. (deposition date: 2016-07-03, release date: 2016-09-07, Last modification date: 2023-10-04)
Primary citation	Torres, M.A.,Hoffarth, E.,Eugenio, L.,Savtchouk, J.,Chen, X.,Morris, J.S.,Facchini, P.J.,Ng, K.K. Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291:23403-23415, 2016 Cited by PubMed: 27573242 DOI: 10.1074/jbc.M116.747261 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation