7VKH
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7VKG
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6AJ9
| The structure of Enterovirus D68 mature virion in complex with Fab 15C5 and 11G1 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | Deposit date: | 2018-08-27 | Release date: | 2018-11-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization Nat Microbiol, 4, 2019
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6AFE
| DJ-1 with compound 7 | Descriptor: | 7-(trifluoromethyl)-1~{H}-indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | Authors: | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | Deposit date: | 2018-08-08 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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3UIM
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6AJ3
| The structure of Enterovirus D68 procapsid | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | Deposit date: | 2018-08-26 | Release date: | 2018-11-07 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization Nat Microbiol, 4, 2019
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6AJ7
| The structure of Enterovirus D68 mature virion in complex with Fab 15C5 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | Deposit date: | 2018-08-27 | Release date: | 2018-11-07 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization Nat Microbiol, 4, 2019
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6AF9
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6AFJ
| DJ-1 with compound 13 | Descriptor: | CHLORIDE ION, Protein/nucleic acid deglycase DJ-1, butyl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate | Authors: | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | Deposit date: | 2018-08-08 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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6AFF
| DJ-1 with compound 8 | Descriptor: | CHLORIDE ION, Protein/nucleic acid deglycase DJ-1, methyl 2,3-bis(oxidanylidene)-1~{H}-indole-7-carboxylate | Authors: | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | Deposit date: | 2018-08-08 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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7VIJ
| Crystal structure of USP7-HUBL domain | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Feng, N, Zeng, K.W. | Deposit date: | 2021-09-27 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy. Sci Adv, 8, 2022
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6AY9
| Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide | Descriptor: | CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ... | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-07 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6AYA
| Structure of the native full-length HIV-1 capsid protein in complex with Nup153 peptide | Descriptor: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-07 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6B2J
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3VLN
| Human Glutathione Transferase O1-1 C32S Mutant in Complex with Ascorbic Acid | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ASCORBIC ACID, ... | Authors: | Brock, J, Board, P.G, Oakley, A.J. | Deposit date: | 2011-12-02 | Release date: | 2012-05-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases. J.Mol.Biol., 420, 2012
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7XPY
| Crystal structure of USP7 in complex with its inhibitor | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7, [(3S,3aR,4R,6Z,9S,10E,11aR)-9-acetyloxy-6-(acetyloxymethyl)-3,10-dimethyl-2-oxidanylidene-3a,4,5,8,9,11a-hexahydro-3H-cyclodeca[b]furan-4-yl] (E)-2-methyl-4-oxidanyl-but-2-enoate | Authors: | Feng, N, Zeng, K.W. | Deposit date: | 2022-05-06 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy. Sci Adv, 8, 2022
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6B2I
| E45A mutant of the HIV-1 capsid protein | Descriptor: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-20 | Release date: | 2018-09-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6B2G
| P38A mutant of HIV-1 capsid protein | Descriptor: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-20 | Release date: | 2018-09-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.407 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6B2H
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6CHC
| JzTx-V toxin peptide, wild-type | Descriptor: | Beta/kappa-theraphotoxin-Cg2a | Authors: | Jordan, J.B. | Deposit date: | 2018-02-22 | Release date: | 2018-05-16 | Method: | SOLUTION NMR | Cite: | Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V. PLoS ONE, 13, 2018
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6CNU
| Crystal Structure of JzTX-V | Descriptor: | BROMIDE ION, GLYCEROL, JzTx-V, ... | Authors: | Min, X, Wang, Z. | Deposit date: | 2018-03-09 | Release date: | 2019-03-06 | Last modified: | 2020-03-04 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis. J. Med. Chem., 61, 2018
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8HMP
| GPR52 with Gs and c17 | Descriptor: | G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Chen, B, Xu, F. | Deposit date: | 2022-12-05 | Release date: | 2023-06-21 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Allosteric coupling between G-protein binding and extracellular ligand binding sites in GPR52 revealed by 19 F-NMR and cryo-electron microscopy. MedComm (2020), 4, 2023
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6B2K
| E45A/R132T mutant of HIV-1 capsid protein | Descriptor: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-20 | Release date: | 2018-09-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6CGW
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7DJZ
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-11-22 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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