7VIJ

Crystal structure of USP7-HUBL domain

Summary for 7VIJ

• Entry DOI: 10.2210/pdb7vij/pdb
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7 (2 entities in total)
• Functional Keywords: protein degradation, ubiquitin-specific protease, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 61800.25

Authors

Feng, N.,Zeng, K.W. (deposition date: 2021-09-27, release date: 2022-08-24, Last modification date: 2023-11-29)

• Primary citation: Zhang, X.W.,Feng, N.,Liu, Y.C.,Guo, Q.,Wang, J.K.,Bai, Y.Z.,Ye, X.M.,Yang, Z.,Yang, H.,Liu, Y.,Yang, M.M.,Wang, Y.H.,Shi, X.M.,Liu, D.,Tu, P.F.,Zeng, K.W.; Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy.; Sci Adv, 8:eabo0789-eabo0789, 2022; PubMed: 35947662; DOI: 10.1126/sciadv.abo0789

Experimental method

X-RAY DIFFRACTION (2.3 Å)