7VKH

Crystal structure of AF9 YEATS domain in complex with hit 2

Summary for 7VKH

• Entry DOI: 10.2210/pdb7vkh/pdb
• Descriptor: Protein AF-9, ~{N}-(3-azanyl-4-chloranyl-phenyl)-2-methoxy-ethanamide, GLYCEROL, ... (4 entities in total)
• Functional Keywords: complex, inhibitor, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 33363.35

Authors

Liu, Y.,Ruan, K. (deposition date: 2021-09-30, release date: 2022-10-05, Last modification date: 2023-11-29)

• Primary citation: Liu, Y.,Jin, R.,Lu, H.,Bian, K.,Wang, R.,Wang, L.,Gao, R.,Zhang, J.,Wu, J.,Yao, X.,Liu, X.,Liu, D.,Wang, X.,Zhang, Z.,Ruan, K.; Fragment-Based Discovery of AF9 YEATS Domain Inhibitors.; Int J Mol Sci, 23:-, 2022; PubMed: 35409252; DOI: 10.3390/ijms23073893

Experimental method

X-RAY DIFFRACTION (2.25 Å)