6O30
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![BU of 6o30 by Molmil](/molmil-images/mine/6o30) | Lipid A transporter MsbA from Salmonella typhimurium | Descriptor: | Lipid A export ATP-binding/permease protein MsbA | Authors: | Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L. | Deposit date: | 2019-02-25 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.47 Å) | Cite: | Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
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2GKI
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![BU of 2gki by Molmil](/molmil-images/mine/2gki) | Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity | Descriptor: | nuclease | Authors: | Kim, Y.R, Kim, J.S, Lee, S.H, Lee, W.R, Sohn, J.N, Chung, Y.C, Shim, H.K, Lee, S.C, Kwon, M.H, Kim, Y.S. | Deposit date: | 2006-04-02 | Release date: | 2006-04-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity. J.Biol.Chem., 281, 2006
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2O5K
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![BU of 2o5k by Molmil](/molmil-images/mine/2o5k) | Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor | Descriptor: | 2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE, Glycogen synthase kinase-3 beta | Authors: | Shin, D, Lee, S.C, Heo, Y.S, Cho, Y.S, Kim, Y.E, Hyun, Y.L, Cho, J.M, Lee, Y.S, Ro, S. | Deposit date: | 2006-12-06 | Release date: | 2007-10-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta Bioorg.Med.Chem.Lett., 17, 2007
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4DIT
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![BU of 4dit by Molmil](/molmil-images/mine/4dit) | |
6BL6
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![BU of 6bl6 by Molmil](/molmil-images/mine/6bl6) | Crystallization of lipid A transporter MsbA from Salmonella typhimurium | Descriptor: | Lipid A export ATP-binding/permease protein MsbA | Authors: | Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C. | Deposit date: | 2017-11-09 | Release date: | 2019-01-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
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5VN9
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![BU of 5vn9 by Molmil](/molmil-images/mine/5vn9) | Structure of bacteriorhodopsin from crystals grown at 4 deg C using GlyNCOC15+4 as an LCP host lipid | Descriptor: | Bacteriorhodopsin | Authors: | Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. | Deposit date: | 2017-04-28 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.594 Å) | Cite: | Chemically Stable Lipids for Membrane Protein Crystallization. Cryst Growth Des, 17, 2017
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5VN7
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![BU of 5vn7 by Molmil](/molmil-images/mine/5vn7) | Structure of bacteriorhodopsin from crystals grown at 20 deg Celcius using GlyNCOC15+4 as an LCP host lipid | Descriptor: | Bacteriorhodopsin | Authors: | Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. | Deposit date: | 2017-04-28 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Chemically Stable Lipids for Membrane Protein Crystallization. Cryst Growth Des, 17, 2017
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1WOU
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![BU of 1wou by Molmil](/molmil-images/mine/1wou) | Crystal Structure of human Trp14 | Descriptor: | thioredoxin -related protein, 14 kDa | Authors: | Woo, J.R, Kim, S.J, Jeong, W, Cho, Y.H, Lee, S.C, Chung, Y.J, Rhee, S.G, Ryu, S.E. | Deposit date: | 2004-08-25 | Release date: | 2004-09-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of cellular redox regulation by human TRP14 J.Biol.Chem., 279, 2004
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4HYX
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![BU of 4hyx by Molmil](/molmil-images/mine/4hyx) | Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-4 DMPC Bicelle | Descriptor: | Bacteriorhodopsin, DECANE, GLYCEROL, ... | Authors: | Lee, S, Stout, C.D, Zhang, Q. | Deposit date: | 2012-11-14 | Release date: | 2013-03-20 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HWL
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![BU of 4hwl by Molmil](/molmil-images/mine/4hwl) | Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-7 DMPC Bicelle | Descriptor: | Bacteriorhodopsin, GLYCEROL, HEPTANE, ... | Authors: | Lee, S, Stout, C.D, Zhang, Q. | Deposit date: | 2012-11-08 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc.Natl.Acad.Sci.USA, 110, 2013
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4OM4
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![BU of 4om4 by Molmil](/molmil-images/mine/4om4) | Crystal structure of CTX A2 from Taiwan Cobra (Naja naja atra) | Descriptor: | Cytotoxin 2 | Authors: | Lin, C.C, Chang, C.I, Wu, W.G. | Deposit date: | 2014-01-26 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface. J.Biol.Chem., 289, 2014
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7UX9
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![BU of 7ux9 by Molmil](/molmil-images/mine/7ux9) | Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA) | Descriptor: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | Authors: | Ipsaro, J.J, Adams, D.W, Joshua-Tor, L. | Deposit date: | 2022-05-05 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. Cell, 186, 2023
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4OM5
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![BU of 4om5 by Molmil](/molmil-images/mine/4om5) | Crystal structure of CTX A4 from Taiwan Cobra (Naja naja atra) | Descriptor: | Cytotoxin 4 | Authors: | Lin, C.C, Chang, C.I, Wu, W.G. | Deposit date: | 2014-01-26 | Release date: | 2014-06-11 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface. J.Biol.Chem., 289, 2014
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3RFS
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![BU of 3rfs by Molmil](/molmil-images/mine/3rfs) | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | Descriptor: | Internalin B, repeat modules, Variable lymphocyte receptor B, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-04-06 | Release date: | 2012-03-14 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering Proc.Natl.Acad.Sci.USA, 109, 2012
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3RFJ
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![BU of 3rfj by Molmil](/molmil-images/mine/3rfj) | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | Descriptor: | Internalin B, repeat modules, Variable lymphocyte receptor, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-04-06 | Release date: | 2012-03-14 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering Proc.Natl.Acad.Sci.USA, 109, 2012
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8P2Z
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![BU of 8p2z by Molmil](/molmil-images/mine/8p2z) | Structure of human SIT1 bound to L-pipecolate (focussed map / refinement) | Descriptor: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P30
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![BU of 8p30 by Molmil](/molmil-images/mine/8p30) | Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate | Descriptor: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P31
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![BU of 8p31 by Molmil](/molmil-images/mine/8p31) | Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate | Descriptor: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2X
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![BU of 8p2x by Molmil](/molmil-images/mine/8p2x) | Structure of human SIT1:ACE2 complex (open PD conformation) | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2W
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![BU of 8p2w by Molmil](/molmil-images/mine/8p2w) | Structure of human SIT1 (focussed map / refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3 | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2Y
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![BU of 8p2y by Molmil](/molmil-images/mine/8p2y) | Structure of human SIT1:ACE2 complex (closed PD conformation) | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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6IWD
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![BU of 6iwd by Molmil](/molmil-images/mine/6iwd) | The PTP domain of human PTPN14 in a complex with the CR3 domain of HPV18 E7 | Descriptor: | CHLORIDE ION, HPV18 E7, PHOSPHATE ION, ... | Authors: | Yun, H.-Y, Kim, S.J, Ku, B. | Deposit date: | 2018-12-05 | Release date: | 2019-07-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus. Plos Biol., 17, 2019
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6TZ8
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![BU of 6tz8 by Molmil](/molmil-images/mine/6tz8) | |
6TZ7
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![BU of 6tz7 by Molmil](/molmil-images/mine/6tz7) | Crystal Structure of Aspergillus fumigatus Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) | Descriptor: | 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... | Authors: | Fox III, D, Horanyi, P.S. | Deposit date: | 2019-08-10 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun, 10, 2019
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6TZ6
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![BU of 6tz6 by Molmil](/molmil-images/mine/6tz6) | Crystal Structure of Candida Albicans Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) | Descriptor: | 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... | Authors: | Fox III, D, Lukacs, C.M. | Deposit date: | 2019-08-10 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun, 10, 2019
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