6IWD

The PTP domain of human PTPN14 in a complex with the CR3 domain of HPV18 E7

Summary for 6IWD

Entry DOI	10.2210/pdb6iwd/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 14, HPV18 E7, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	oncoprotein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	41637.42
Authors	Yun, H.-Y.,Kim, S.J.,Ku, B. (deposition date: 2018-12-05, release date: 2019-07-31, Last modification date: 2023-11-22)
Primary citation	Yun, H.Y.,Kim, M.W.,Lee, H.S.,Kim, W.,Shin, J.H.,Kim, H.,Shin, H.C.,Park, H.,Oh, B.H.,Kim, W.K.,Bae, K.H.,Lee, S.C.,Lee, E.W.,Ku, B.,Kim, S.J. Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus. Plos Biol., 17:e3000367-e3000367, 2019 Cited by PubMed: 31323018 DOI: 10.1371/journal.pbio.3000367 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation