6IWD
The PTP domain of human PTPN14 in a complex with the CR3 domain of HPV18 E7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 14 | polymer | 303 | 35063.3 | 1 | UniProt (Q15678) Pfam (PF00102) | Homo sapiens (Human) | Protein-tyrosine phosphatase pez |
| 2 | B (B) | HPV18 E7 | polymer | 55 | 6283.3 | 1 | UniProt (Q76Z96) Pfam (PF00527) UniProt (by SIFTS) (P06788) | Human papillomavirus type 18 | |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | F (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A: 886 - 1187 (UniProt: Q15678)
B: 54 - 105 (UniProt: Q76Z96)
| PDB | External Database | Details |
|---|---|---|
| Met 885 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | expression tag |
| His 52 | - | expression tag |
| Met 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41346.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 290.8 | |
| All* | Total formula weight | 41637.4 |
