6IWD
The PTP domain of human PTPN14 in a complex with the CR3 domain of HPV18 E7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 A 1202 |
| Chain | Residue |
| A | LYS956 |
| A | ARG1016 |
| A | THR1017 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 1203 |
| Chain | Residue |
| A | LYS1025 |
| A | LEU1026 |
| A | ARG1045 |
| A | HOH1427 |
| B | ARG71 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 201 |
| Chain | Residue |
| B | CYS68 |
| B | CYS98 |
| B | CYS101 |
| B | CYS65 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG |
| Chain | Residue | Details |
| A | VAL1119-GLY1129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
