6MJI
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![BU of 6mji by Molmil](/molmil-images/mine/6mji) | Crystal structure of the mCD1d/xxs (JJ304) /iNKTCR ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Zajonc, D.M, Bitra, A, Janssens, J. | Deposit date: | 2018-09-20 | Release date: | 2019-01-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem, 14, 2019
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6MIY
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![BU of 6miy by Molmil](/molmil-images/mine/6miy) | Crystal structure of the mCD1d/xxa (JJ239)/iNKTCR ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Zajonc, D.M, Bitra, A, Janssens, J. | Deposit date: | 2018-09-20 | Release date: | 2019-01-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem, 14, 2019
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6MJJ
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![BU of 6mjj by Molmil](/molmil-images/mine/6mjj) | Crystal structure of the mCD1d/xxm (JJ290) /iNKTCR ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M, Bitra, A, Janssens, J. | Deposit date: | 2018-09-21 | Release date: | 2019-01-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem, 14, 2019
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1CE0
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![BU of 1ce0 by Molmil](/molmil-images/mine/1ce0) | |
7WH1
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![BU of 7wh1 by Molmil](/molmil-images/mine/7wh1) | structure of C elegans BCMO-2 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7WH0
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![BU of 7wh0 by Molmil](/molmil-images/mine/7wh0) | structure of C elegans BCMO-1 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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5V21
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![BU of 5v21 by Molmil](/molmil-images/mine/5v21) | |
7WCM
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![BU of 7wcm by Molmil](/molmil-images/mine/7wcm) | Cryo-EM structure of GPR119-Gs Complex with small molecule agonist MBX-2982 | Descriptor: | 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Qiao, A.N, Wu, S, Ye, S. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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3LM0
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![BU of 3lm0 by Molmil](/molmil-images/mine/3lm0) | Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Serine/threonine-protein kinase 17B, ... | Authors: | Ugochukwu, E, Soundararajan, M, Rellos, P, Fedorov, O, Phillips, C, Wang, J, Hapka, E, Filippakopoulos, P, Chaikuad, A, Pike, A.C.W, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-01-29 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: |
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7WCN
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![BU of 7wcn by Molmil](/molmil-images/mine/7wcn) | Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453 | Descriptor: | Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Qiao, A.N, Wu, S, Ye, S. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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3LM5
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![BU of 3lm5 by Molmil](/molmil-images/mine/3lm5) | Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Serine/threonine-protein kinase 17B | Authors: | Ugochukwu, E, Soundararajan, M, Rellos, P, Fedorov, O, Phillips, C, Wang, J, Hapka, E, Filippakopoulos, P, Chaikuad, A, Pike, A.C.W, Carpenter, L, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-01-29 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation. J.Med.Chem., 63, 2020
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3TA3
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![BU of 3ta3 by Molmil](/molmil-images/mine/3ta3) | Structure of the mouse CD1d-Glc-DAG-s2-iNKT TCR complex | Descriptor: | (2S)-1-(alpha-D-glucopyranosyloxy)-3-(hexadecanoyloxy)propan-2-yl (11Z)-octadec-11-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Girardi, E, Yu, E.D, Zajonc, D.M. | Deposit date: | 2011-08-03 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells. Plos Biol., 9, 2011
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7WWF
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![BU of 7wwf by Molmil](/molmil-images/mine/7wwf) | Crystal structure of BioH3 from Mycolicibacterium smegmatis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Esterase | Authors: | Yang, J, Xu, Y.C, Gan, J.H, Feng, Y.J. | Deposit date: | 2022-02-12 | Release date: | 2022-07-06 | Last modified: | 2023-01-18 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18, 2022
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7X81
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![BU of 7x81 by Molmil](/molmil-images/mine/7x81) | The crystal structure of PloI4-C16M/D46A/I137V in complex with exo-2+2 adduct | Descriptor: | (4S,4aS,6aR,8R,9R,11E,12aR,14aS,17E,18aR,18bR)-9-ethyl-4,8,19-trihydroxy-11,12a,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,12a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)cyclobuta[b]naphtho[2,1-j][1]azacyclotetradecine-16,18(1H,15H)-dione, PloI4 | Authors: | Li, M, Pan, L.F. | Deposit date: | 2022-03-10 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions. Nat.Chem., 15, 2023
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7X80
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![BU of 7x80 by Molmil](/molmil-images/mine/7x80) | |
7X7Z
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![BU of 7x7z by Molmil](/molmil-images/mine/7x7z) | |
7X86
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![BU of 7x86 by Molmil](/molmil-images/mine/7x86) | The crystal structure of PloI4-F124L in complex with endo-4+2 adduct | Descriptor: | (4S,4aS,6aR,8R,9R,10aS,13S,14aS,18aR,18bR,E)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,10a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)benzo[b]naphtho[2,1-h][1]azacyclododecine-16,18(1H,15H)-dione, PloI4 | Authors: | Li, M, Pan, L.F. | Deposit date: | 2022-03-11 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions. Nat.Chem., 15, 2023
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5VCL
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![BU of 5vcl by Molmil](/molmil-images/mine/5vcl) | Structure of the Qdm peptide bound to Qa-1a | Descriptor: | Beta-2-microglobulin, GLYCEROL, H2-T23 protein, ... | Authors: | Ying, G, Zajonc, D.M. | Deposit date: | 2017-03-31 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of Qa-1a with bound Qa-1 determinant modifier peptide. PLoS ONE, 12, 2017
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5WVF
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![BU of 5wvf by Molmil](/molmil-images/mine/5wvf) | |
5V22
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![BU of 5v22 by Molmil](/molmil-images/mine/5v22) | |
5WV8
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![BU of 5wv8 by Molmil](/molmil-images/mine/5wv8) | |
5WQC
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![BU of 5wqc by Molmil](/molmil-images/mine/5wqc) | Crystal structure of human orexin 2 receptor bound to the selective antagonist EMPA determined by the synchrotron light source at SPring-8. | Descriptor: | N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, ... | Authors: | Suno, R, Hirata, K, Yamashita, K, Tsujimoto, H, Sasanuma, M, Horita, S, Yamamoto, M, Rosenbaum, D.M, Iwata, S, Shimamura, T, Kobayashi, T. | Deposit date: | 2016-11-25 | Release date: | 2017-11-29 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA Structure, 26, 2018
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5WV9
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![BU of 5wv9 by Molmil](/molmil-images/mine/5wv9) | |
5T0K
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![BU of 5t0k by Molmil](/molmil-images/mine/5t0k) | Structure of G9a SET-domain with H3K9M mutant peptide and SAM | Descriptor: | H3K9 mutant peptide, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... | Authors: | Xu, K, Tong, L. | Deposit date: | 2016-08-16 | Release date: | 2016-10-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading. Elife, 5, 2016
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7VZR
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![BU of 7vzr by Molmil](/molmil-images/mine/7vzr) | Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c (the smaller form) | Descriptor: | BACTERIOCHLOROPHYLL A, CALCIUM ION, CHLOROPHYLL A, ... | Authors: | Huang, G.Q, Dong, S.S, Qin, X.C, Sui, S.F. | Deposit date: | 2021-11-16 | Release date: | 2022-12-28 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.22 Å) | Cite: | Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c Nat Commun, 13, 2022
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