6MJJ

Crystal structure of the mCD1d/xxm (JJ290) /iNKTCR ternary complex

Summary for 6MJJ

Entry DOI	10.2210/pdb6mjj/pdb
Descriptor	T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, N-[(2S,3S,4R)-1-({4-O-[(3,4-dichlorophenyl)methyl]-alpha-D-galactopyranosyl}oxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanamide, Beta-chain,Tcell receptor chain,T cell receptor beta constant 2, CHIMERIC PROTEIN, ... (11 entities in total)
Functional Keywords	mhc-fold, ig-fold, glycolipid antigen presentation, t cell receptor, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	97736.97
Authors	Zajonc, D.M.,Bitra, A.,Janssens, J. (deposition date: 2018-09-21, release date: 2019-01-09, Last modification date: 2023-10-11)
Primary citation	Janssens, J.,Bitra, A.,Wang, J.,Decruy, T.,Venken, K.,van der Eycken, J.,Elewaut, D.,Zajonc, D.M.,van Calenbergh, S. 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem, 14:147-168, 2019 Cited by PubMed: 30556652 DOI: 10.1002/cmdc.201800649 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation