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7WWF

Crystal structure of BioH3 from Mycolicibacterium smegmatis

Summary for 7WWF
Entry DOI10.2210/pdb7wwf/pdb
DescriptorEsterase, DI(HYDROXYETHYL)ETHER, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordsmycolicibacterium smegmatis, bioh3, crystal, biosynthetic protein
Biological sourceMycolicibacterium smegmatis MC2 155
Total number of polymer chains6
Total formula weight182709.52
Authors
Yang, J.,Xu, Y.C.,Gan, J.H.,Feng, Y.J. (deposition date: 2022-02-12, release date: 2022-07-06, Last modification date: 2023-01-18)
Primary citationXu, Y.,Yang, J.,Li, W.,Song, S.,Shi, Y.,Wu, L.,Sun, J.,Hou, M.,Wang, J.,Jia, X.,Zhang, H.,Huang, M.,Lu, T.,Gan, J.,Feng, Y.
Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target.
Plos Pathog., 18:e1010615-e1010615, 2022
Cited by
PubMed: 35816546
DOI: 10.1371/journal.ppat.1010615
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.27 Å)
Structure validation

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