2GDN
 
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2H9I
 | | Mycobacterium tuberculosis InhA bound with ETH-NAD adduct | | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | | Authors: | Wang, F, Sacchettini, J.C. | | Deposit date: | 2006-06-09 | | Release date: | 2007-01-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism of thioamide drug action against tuberculosis and leprosy.
J.Exp.Med., 204, 2007
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2HVC
 | | The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226 | | Descriptor: | 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE, Androgen receptor | | Authors: | Wang, F, Liu, X.-Q, Li, H, Liang, K.-N, Miner, J.N, Hong, M, Kallel, E.A, van Oeveren, A, Zhi, L, Jiang, T. | | Deposit date: | 2006-07-28 | | Release date: | 2007-07-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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2I46
 | | Crystal structure of human TPP1 | | Descriptor: | Adrenocortical dysplasia protein homolog | | Authors: | Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M. | | Deposit date: | 2006-08-21 | | Release date: | 2006-11-28 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The POT1-TPP1 telomere complex is a telomerase processivity factor.
Nature, 445, 2007
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2K86
 | | Solution Structure of FOXO3a Forkhead domain | | Descriptor: | Forkhead box protein O3 | | Authors: | Wang, F, Marshall, C.B, Li, G, Plevin, M.J, Ikura, M. | | Deposit date: | 2008-09-02 | | Release date: | 2008-10-14 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53.
J.Mol.Biol., 384, 2008
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7DE0
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7DS7
 | | The Crystal Structure of Leaf-branch compost cutinase from Biortus. | | Descriptor: | CITRIC ACID, GLYCEROL, IMIDAZOLE, ... | | Authors: | Wang, F, Lv, Z, Cheng, W, Lin, D, Chu, F, Xu, X, Tan, J. | | Deposit date: | 2020-12-30 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The Crystal Structure of Leaf-branch compost cutinase from Biortus.
To Be Published
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2LQI
 | | NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation) | | Descriptor: | CREB-binding protein, Forkhead box O3 | | Authors: | Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. | | Deposit date: | 2012-03-06 | | Release date: | 2012-05-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2LQH
 | | NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation) | | Descriptor: | CREB-binding protein, Forkhead box O3 | | Authors: | Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. | | Deposit date: | 2012-03-06 | | Release date: | 2012-05-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2NTV
 | | Mycobacterium leprae InhA bound with PTH-NAD adduct | | Descriptor: | Enoyl-[ACP] reductase, {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | | Authors: | Wang, F, Sacchettini, J.C. | | Deposit date: | 2006-11-08 | | Release date: | 2007-01-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mechanism of thioamide drug action against tuberculosis and leprosy.
J.Exp.Med., 204, 2007
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7CMR
 | | The Crystal Structure of human MYST1 from Biortus. | | Descriptor: | GLYCEROL, Histone acetyltransferase KAT8, ZINC ION | | Authors: | Wang, F, Lin, D, Lv, Z, Xu, X, Tan, J, Shang, H. | | Deposit date: | 2020-07-28 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Crystal Structure of human MYST1 from Biortus.
To Be Published
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7C62
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7CM2
 | | The Crystal Structure of human USP7 USP domain from Biortus | | Descriptor: | GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 7 | | Authors: | Wang, F, Cheng, W, Lv, Z, Lin, D, Zhu, B, Miao, Q, Bao, X, Shang, H. | | Deposit date: | 2020-07-24 | | Release date: | 2020-08-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The Crystal Structure of human USP7 USP domain from Biortus.
To Be Published
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7CML
 | | The Crystal Structure of human JNK2 from Biortus. | | Descriptor: | Mitogen-activated protein kinase 9 | | Authors: | Wang, F, Lin, D, Cheng, W, Miao, Q, Huang, Y, Shang, H. | | Deposit date: | 2020-07-28 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The Crystal Structure of human JNK2 from Biortus.
To Be Published
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7CVP
 | | The Crystal Structure of human PHGDH from Biortus. | | Descriptor: | D-3-phosphoglycerate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, F, Lv, Z, Cheng, W, Lin, D, Miao, Q, Huang, Y. | | Deposit date: | 2020-08-26 | | Release date: | 2020-09-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Crystal Structure of human PHGDH from Biortus.
To Be Published
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7C4I
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7CA4
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7D4A
 | | The Crystal Structure of human JMJD2A Tudor domain from Biortus | | Descriptor: | Lysine-specific demethylase 4A, SULFATE ION | | Authors: | Wang, F, Lv, Z, Cheng, W, Lin, D, Ju, C, Bao, X, Zhu, B. | | Deposit date: | 2020-09-23 | | Release date: | 2020-10-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | The Crystal Structure of human JMJD2A from Biortus.
To Be Published
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7DSF
 | | The Crystal Structure of human SPR from Biortus. | | Descriptor: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase, ... | | Authors: | Wang, F, Lv, Z, Cheng, W, Lin, D, Meng, Q, Zhang, B, Huang, Y. | | Deposit date: | 2020-12-31 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Crystal Structure of human SPR from Biortus.
To Be Published
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7D2C
 | | The Crystal Structure of human PARP14 from Biortus. | | Descriptor: | CHLORIDE ION, GLYCEROL, Protein mono-ADP-ribosyltransferase PARP14 | | Authors: | Wang, F, Miao, Q, Lv, Z, Cheng, W, Lin, D, Xu, X, Tan, J. | | Deposit date: | 2020-09-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | The Crystal Structure of human PARP14 from Biortus.
To Be Published
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7ESE
 | | The Crystal Structure of human DHFR from Biortus | | Descriptor: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Wang, F, Cheng, W, Xu, C, Qi, J, Bao, X, Miao, Q. | | Deposit date: | 2021-05-10 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Crystal Structure of human DHFR from Biortus
To Be Published
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5D6Y
 | | Crystal structure of double tudor domain of human lysine demethylase KDM4A complexed with histone H3K23me3 | | Descriptor: | Lysine-specific demethylase 4A, peptide H3K23me3 (19-28) | | Authors: | Wang, F, Su, Z, Miller, M.D, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | Deposit date: | 2015-08-13 | | Release date: | 2016-02-10 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.287 Å) | | Cite: | Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
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5D6W
 | | Crystal structure of double tudor domain of human lysine demethylase KDM4A | | Descriptor: | Lysine-specific demethylase 4A, S,R MESO-TARTARIC ACID | | Authors: | Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | Deposit date: | 2015-08-13 | | Release date: | 2015-11-25 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.992 Å) | | Cite: | Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
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5D6X
 | | Crystal structure of double tudor domain of human lysine demethylase KDM4A | | Descriptor: | Lysine-specific demethylase 4A, SULFATE ION | | Authors: | Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | Deposit date: | 2015-08-13 | | Release date: | 2015-11-25 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.153 Å) | | Cite: | Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
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6X5I
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