2H9I
Mycobacterium tuberculosis InhA bound with ETH-NAD adduct
Summary for 2H9I
Entry DOI | 10.2210/pdb2h9i/pdb |
Related | 1ZID |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-ETHYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}METHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE (3 entities in total) |
Functional Keywords | inha, ethionamide, eth, tuberculosis, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 29192.15 |
Authors | Wang, F.,Sacchettini, J.C. (deposition date: 2006-06-09, release date: 2007-01-30, Last modification date: 2023-08-30) |
Primary citation | Wang, F.,Langley, R.,Gulten, G.,Dover, L.G.,Besra, G.S.,Jacobs, W.R.,Sacchettini, J.C. Mechanism of thioamide drug action against tuberculosis and leprosy. J.Exp.Med., 204:73-78, 2007 Cited by PubMed: 17227913DOI: 10.1084/jem.20062100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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