Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
A | 0005504 | molecular_function | fatty acid binding |
A | 0005886 | cellular_component | plasma membrane |
A | 0006633 | biological_process | fatty acid biosynthetic process |
A | 0009274 | cellular_component | peptidoglycan-based cell wall |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0030497 | biological_process | fatty acid elongation |
A | 0046677 | biological_process | response to antibiotic |
A | 0050343 | molecular_function | trans-2-enoyl-CoA reductase (NADH) activity |
A | 0070403 | molecular_function | NAD+ binding |
A | 0071768 | biological_process | mycolic acid biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 31 |
Details | BINDING SITE FOR RESIDUE EAD A 300 |
Chain | Residue |
A | GLY14 |
A | SER94 |
A | ILE95 |
A | GLY96 |
A | ILE122 |
A | MET147 |
A | ASP148 |
A | PHE149 |
A | MET155 |
A | TYR158 |
A | LYS165 |
A | ILE15 |
A | ALA191 |
A | GLY192 |
A | PRO193 |
A | ILE194 |
A | THR196 |
A | MET199 |
A | TRP222 |
A | HOH302 |
A | HOH315 |
A | HOH320 |
A | ILE16 |
A | HOH325 |
A | HOH330 |
A | SER20 |
A | ILE21 |
A | PHE41 |
A | LEU63 |
A | ASP64 |
A | VAL65 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER20 | |
A | ASP64 | |
A | ILE95 | |
A | LYS165 | |
A | ILE194 | |
Chain | Residue | Details |
A | TYR158 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | SITE: May act as an intermediate that passes the hydride ion from NADH to the substrate => ECO:0000305|PubMed:10336454 |
Chain | Residue | Details |
A | PHE149 | |
Chain | Residue | Details |
A | TYR158 | |
Chain | Residue | Details |
A | THR266 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
A | TYR158 | |
A | LYS165 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1qsg |
Chain | Residue | Details |
A | MET161 | |
A | LYS165 | |