2HVC

The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226

Summary for 2HVC

Entry DOI	10.2210/pdb2hvc/pdb
Descriptor	Androgen receptor, 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE (3 entities in total)
Functional Keywords	complexed with lgd2226, dna-binding, steroid-binding, ligand binding protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P10275
Total number of polymer chains	1
Total formula weight	29541.43
Authors	Wang, F.,Liu, X.-Q.,Li, H.,Liang, K.-N.,Miner, J.N.,Hong, M.,Kallel, E.A.,van Oeveren, A.,Zhi, L.,Jiang, T. (deposition date: 2006-07-28, release date: 2007-07-31, Last modification date: 2023-10-25)
Primary citation	Wang, F.,Liu, X.-Q.,Li, H.,Liang, K.-N.,Miner, J.N.,Hong, M.,Kallel, E.A.,van Oeveren, A.,Zhi, L.,Jiang, T. Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226 ACTA CRYSTALLOGR.,SECT.F, 62:1067-1071, 2006 Cited by PubMed: 17077481 DOI: 10.1107/S1744309106039340 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation