6I4B
 
 | | Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with 3-Hydroxy-1-methyl-5-((3-(trifluoromethyl)phenoxy)methyl)-1H-pyrazole-4-carboxylic acid | | Descriptor: | 1-methyl-3-oxidanyl-5-[[3-(trifluoromethyl)phenoxy]methyl]pyrazole-4-carboxylic acid, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Goyal, P, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S. | | Deposit date: | 2018-11-09 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Eur J Med Chem, 163, 2018
|
|
8RD5
 | | Crystal structure of Kemp Eliminase HG3.R5 with bound transition state analog 6-nitrobenzotriazole | | Descriptor: | 6-NITROBENZOTRIAZOLE, ACETATE ION, Endo-1,4-beta-xylanase, ... | | Authors: | Schaub, D, Schwander, T, Hueppi, S, Buller, R.M. | | Deposit date: | 2023-12-07 | | Release date: | 2024-09-04 | | Last modified: | 2024-09-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Enriching productive mutational paths accelerates enzyme evolution.
Nat.Chem.Biol., 2024
|
|
8SHI
 | | Valpha3S1 Vbeta13S1 HLA C 0602 VRSRRCLRL | | Descriptor: | Beta-2-microglobulin, MHC class I antigen (Fragment), T cell receptor alpha, ... | | Authors: | Littler, D.R, Anand, S, Vivian, J.P, Rossjohn, J. | | Deposit date: | 2023-04-14 | | Release date: | 2023-06-28 | | Last modified: | 2023-07-26 | | Method: | X-RAY DIFFRACTION (2.90001726 Å) | | Cite: | Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02.
J.Biol.Chem., 299, 2023
|
|
8SGD
 | | Crystal Structure of CDC3(G) - CDC10(Delta 1-10) heterocomplex from Saccharomyces cerevisiae | | Descriptor: | CDC10 isoform 1, CDC3 isoform 1, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Saladino, G.C.R, Leonardo, D.A, Pereira, H.M, Garratt, R.C. | | Deposit date: | 2023-04-12 | | Release date: | 2023-06-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly.
J.Struct.Biol., 215, 2023
|
|
8Q91
 | | Structure of the human 20S U5 snRNP core | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Schneider, S, Galej, W.P. | | Deposit date: | 2023-08-19 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of the human 20S U5 snRNP.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8RC0
 | | Structure of the human 20S U5 snRNP | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Schneider, S, Galej, W.P. | | Deposit date: | 2023-12-05 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of the human 20S U5 snRNP.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8QAT
 | |
6I55
 | | Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with N-(2,2-Diphenylethyl)-4-hydroxy-1,2,5-thiadiazole-3-carboxamide | | Descriptor: | Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, N-(2,2-Diphenylethyl)-4-hydroxy-1,2,5-thiadiazole-3-carboxamide, ... | | Authors: | Goyal, P, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S. | | Deposit date: | 2018-11-12 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Eur J Med Chem, 163, 2018
|
|
6HLF
 | | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant - K32A | | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, R-specific alcohol dehydrogenase | | Authors: | Hermann, J, Nowotny, P, Schneider, S, Hekmat, D, Weuster-Botz, D. | | Deposit date: | 2018-09-11 | | Release date: | 2018-12-12 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Rational Crystal Contact Engineering of Lactobacillus brevis Alcohol Dehydrogenase To Promote Technical Protein Crystallization
Cryst.Growth Des., 2019
|
|
6Y3X
 | |
8CEA
 | | Cytochrome c maturation complex CcmABCD, E154Q | | Descriptor: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | | Authors: | Ilcu, L, Zhang, L, Einsle, O. | | Deposit date: | 2023-02-01 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation.
Nat Commun, 14, 2023
|
|
8CE1
 | | Cytochrome c maturation complex CcmABCD | | Descriptor: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | | Authors: | Ilcu, L, Zhang, L, Einsle, O. | | Deposit date: | 2023-02-01 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation.
Nat Commun, 14, 2023
|
|
8CE5
 | | Cytochrome c maturation complex CcmABCD, E154Q, ATP-bound | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | Authors: | Ilcu, L, Zhang, L, Einsle, O. | | Deposit date: | 2023-02-01 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation.
Nat Commun, 14, 2023
|
|
8CE8
 | | Cytochrome c maturation complex CcmABCDE | | Descriptor: | Cytochrome c biogenesis ATP-binding export protein CcmA, Cytochrome c-type biogenesis protein CcmE, Heme exporter protein B, ... | | Authors: | Ilcu, L, Zhang, L, Einsle, O. | | Deposit date: | 2023-02-01 | | Release date: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.81 Å) | | Cite: | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation.
Nat Commun, 14, 2023
|
|
3QQP
 | | Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with Urea Inhibitor | | Descriptor: | 3,4-dihydroquinolin-1(2H)-yl[4-(1H-imidazol-5-yl)piperidin-1-yl]methanone, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Loenze, P, Schimanski-Breves, S, Engel, C.K. | | Deposit date: | 2011-02-16 | | Release date: | 2012-02-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11beta-hydroxysteroid-dehydrogenase type 1.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
1JVP
 | |
1LKT
 | | CRYSTAL STRUCTURE OF THE HEAD-BINDING DOMAIN OF PHAGE P22 TAILSPIKE PROTEIN | | Descriptor: | TAILSPIKE PROTEIN | | Authors: | Steinbacher, S. | | Deposit date: | 1997-10-17 | | Release date: | 1998-01-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Phage P22 tailspike protein: crystal structure of the head-binding domain at 2.3 A, fully refined structure of the endorhamnosidase at 1.56 A resolution, and the molecular basis of O-antigen recognition and cleavage.
J.Mol.Biol., 267, 1997
|
|
3QM0
 | | Crystal structure of RTT109-AC-CoA complex | | Descriptor: | ACETYL COENZYME *A, Histone acetyltransferase RTT109, MERCURY (II) ION | | Authors: | Tang, Y, Marmorstein, R. | | Deposit date: | 2011-02-03 | | Release date: | 2011-02-16 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.
Nat.Struct.Mol.Biol., 15, 2008
|
|
2M8O
 | | NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in DPC | | Descriptor: | Transmembrane protein gp41 | | Authors: | Serrano, S, Huarte, N, Nieva, J.L, Jimenez, M. | | Deposit date: | 2013-05-23 | | Release date: | 2014-01-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope: IMPLICATIONS FOR ANTIBODY RECOGNITION MECHANISM AND IMMUNOGEN DESIGN.
J.Biol.Chem., 289, 2014
|
|
2M8M
 | | NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol | | Descriptor: | Transmembrane protein gp41 | | Authors: | Serrano, S, Huarte, N, Nieva, J.L, Jimenez, M. | | Deposit date: | 2013-05-23 | | Release date: | 2014-01-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope: IMPLICATIONS FOR ANTIBODY RECOGNITION MECHANISM AND IMMUNOGEN DESIGN.
J.Biol.Chem., 289, 2014
|
|
6SZB
 | |
1ZFP
 | |
6SZA
 | |
1TZE
 | |
2ALE
 | | Crystal structure of yeast RNA splicing factor Snu13p | | Descriptor: | MAGNESIUM ION, NHP2/L7aE family protein YEL026W | | Authors: | Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T. | | Deposit date: | 2005-08-05 | | Release date: | 2006-10-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.
Biochem.Biophys.Res.Commun., 360, 2007
|
|
