2M8O

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in DPC

Summary for 2M8O

• Entry DOI: 10.2210/pdb2m8o/pdb
• Related: 2m8m
• NMR Information: BMRB: 19263
• Descriptor: Transmembrane protein gp41 (1 entity in total)
• Functional Keywords: hiv-1 gp41 protein, neutralizing epitope, peptide vaccine, viral protein
• Biological source: Human immunodeficiency virus type 1 (HIV-1)
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05878
• Total number of polymer chains: 1
• Total formula weight: 3656.11

Authors

Serrano, S.,Huarte, N.,Nieva, J.L.,Jimenez, M. (deposition date: 2013-05-23, release date: 2014-01-22, Last modification date: 2023-06-14)

• Primary citation: Serrano, S.,Araujo, A.,Apellaniz, B.,Bryson, S.,Carravilla, P.,de la Arada, I.,Huarte, N.,Rujas, E.,Pai, E.F.,Arrondo, J.L.,Domene, C.,Jimenez, M.A.,Nieva, J.L.; Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope: IMPLICATIONS FOR ANTIBODY RECOGNITION MECHANISM AND IMMUNOGEN DESIGN.; J.Biol.Chem., 289:6565-6580, 2014; PubMed: 24429284; DOI: 10.1074/jbc.M113.527747

Experimental method

SOLUTION NMR