8RD5

Crystal structure of Kemp Eliminase HG3.R5 with bound transition state analog 6-nitrobenzotriazole

Summary for 8RD5

Entry DOI	10.2210/pdb8rd5/pdb
Descriptor	Endo-1,4-beta-xylanase, 6-NITROBENZOTRIAZOLE, GLYCEROL, ... (5 entities in total)
Functional Keywords	kemp eliminase, 6-nitrobenzotriazole, endo-1, 4-beta-xylanase, hydrolase
Biological source	Thermoascus aurantiacus
Total number of polymer chains	2
Total formula weight	69661.04
Authors	Schaub, D.,Schwander, T.,Hueppi, S.,Buller, R.M. (deposition date: 2023-12-07, release date: 2024-09-04, Last modification date: 2024-09-25)
Primary citation	Patsch, D.,Schwander, T.,Voss, M.,Schaub, D.,Huppi, S.,Eichenberger, M.,Stockinger, P.,Schelbert, L.,Giger, S.,Peccati, F.,Jimenez-Oses, G.,Mutny, M.,Krause, A.,Bornscheuer, U.T.,Hilvert, D.,Buller, R.M. Enriching productive mutational paths accelerates enzyme evolution. Nat.Chem.Biol., 2024 Cited by PubMed: 39261644 DOI: 10.1038/s41589-024-01712-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation