5XTF
 
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5ZHF
 | | Structure of VanYB unbound | | Descriptor: | D-alanyl-D-alanine carboxypeptidase, GLYCEROL, TETRAETHYLENE GLYCOL, ... | | Authors: | Kim, H.S, Hahn, H. | | Deposit date: | 2018-03-13 | | Release date: | 2018-09-05 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for the substrate recognition of peptidoglycan pentapeptides by Enterococcus faecalis VanYB.
Int. J. Biol. Macromol., 119, 2018
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6W30
 | | Protein Tyrosine Phosphatase 1B Bound to Amorphadiene | | Descriptor: | Amorphadiene, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Sarkar, A, Kim, E.Y, Hongdusit, A, Sankaran, B, Fox, J. | | Deposit date: | 2020-03-08 | | Release date: | 2021-05-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products.
Acs Synth Biol, 10, 2021
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5Z5A
 | | Crystal structure of Tk-PTP in the active form | | Descriptor: | Protein-tyrosine phosphatase, VANADATE ION | | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | | Deposit date: | 2018-01-17 | | Release date: | 2018-07-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1
PLoS ONE, 13, 2018
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4WXR
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1Y4U
 | | Conformation rearrangement of heat shock protein 90 upon ADP binding | | Descriptor: | Chaperone protein htpG | | Authors: | Huai, Q, Wang, H, Liu, Y, Kim, H, Toft, D, Ke, H. | | Deposit date: | 2004-12-01 | | Release date: | 2005-04-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
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2G95
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2G97
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2G96
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7LAW
 | | crystal structure of GITR complex with GITR-L | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18 | | Authors: | Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H. | | Deposit date: | 2021-01-07 | | Release date: | 2022-03-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.752 Å) | | Cite: | An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy.
Nat Cancer, 3, 2022
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5K1A
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5K16
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5K1C
 | | Crystal structure of the UAF1/WDR20/USP12 complex | | Descriptor: | PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ... | | Authors: | Li, H, D'Andrea, A.D, Zheng, N. | | Deposit date: | 2016-05-18 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
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5K1B
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6YEJ
 | | Cryo-EM structure of the Full-length disease type human Huntingtin | | Descriptor: | Huntingtin | | Authors: | Tame, G, Jung, T, Dal Perraro, M, Hebert, H, Song, J. | | Deposit date: | 2020-03-24 | | Release date: | 2020-12-16 | | Method: | ELECTRON MICROSCOPY (18.200001 Å) | | Cite: | The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain.
Structure, 28, 2020
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5K19
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5YSS
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3P2F
 | | Crystal structure of TofI in an apo form | | Descriptor: | AHL synthase | | Authors: | Yu, S, Rhee, S. | | Deposit date: | 2010-10-02 | | Release date: | 2011-07-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
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5X42
 | | Structure of DotL(590-659)-DotN derived from Legionella pneumophila | | Descriptor: | DotN, IcmJ (DotN), IcmO (DotL), ... | | Authors: | Kwak, M.J, Kim, J.D, Oh, B.H. | | Deposit date: | 2017-02-09 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Architecture of the type IV coupling protein complex of Legionella pneumophila
Nat Microbiol, 2, 2017
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6XNG
 | | MHC-like protein complex structure | | Descriptor: | (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | Authors: | Thirunavukkarasu, P, Le Nours, J, Rossjohn, J. | | Deposit date: | 2020-07-02 | | Release date: | 2021-11-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
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3P2H
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6IJR
 | | Human PPARgamma ligand binding domain complexed with SB1495 | | Descriptor: | 16 mer peptide from Nuclear receptor coactivator 1, N-{[3-({[(1S,2R)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Peroxisome proliferator-activated receptor gamma | | Authors: | Jang, J.Y, Han, B.W. | | Deposit date: | 2018-10-11 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.
Sci Rep, 9, 2019
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6IJS
 | | Human PPARgamma ligand binding domain complexed with SB1494 | | Descriptor: | 16-mer peptide from Nuclear receptor coactivator 1, N-{[3-({[(1R,2S)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Peroxisome proliferator-activated receptor gamma | | Authors: | Jang, J.Y, Han, B.W. | | Deposit date: | 2018-10-11 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.
Sci Rep, 9, 2019
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5X1U
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6JQ7
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