3P2H

Crystal structure of TofI in a ternary complex with an inhibitor and MTA

Summary for 3P2H

• Entry DOI: 10.2210/pdb3p2h/pdb
• Related: 3P2F
• Descriptor: AHL synthase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, N-(3-oxocyclohex-1-en-1-yl)octanamide, ... (4 entities in total)
• Functional Keywords: synthase, acyl-acp binding, sam binding, signaling protein-inhibitor-mta complex, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Burkholderia glumae (Pseudomonas glumae)
• Total number of polymer chains: 1
• Total formula weight: 22753.93

Authors

Yu, S.,Rhee, S. (deposition date: 2010-10-02, release date: 2011-07-06, Last modification date: 2024-03-20)

• Primary citation: Chung, J.,Goo, E.,Yu, S.,Choi, O.,Lee, J.,Kim, J.,Kim, H.,Igarashi, J.,Suga, H.,Moon, J.S.,Hwang, I.,Rhee, S.; Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase; Proc.Natl.Acad.Sci.USA, 108:12089-12094, 2011; PubMed: 21730159; DOI: 10.1073/pnas.1103165108

Experimental method

X-RAY DIFFRACTION (2 Å)