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3P2H

Crystal structure of TofI in a ternary complex with an inhibitor and MTA

Functional Information from GO Data
ChainGOidnamespacecontents
A0007165biological_processsignal transduction
A0009372biological_processquorum sensing
A0016740molecular_functiontransferase activity
A0061579molecular_functionN-acyl homoserine lactone synthase activity
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE MTA A 204
ChainResidue
AGLN2
ATRP33
AASP45
AGLN46
ALEU78
APHE83
AARG104
AHOH231
AHOH253

site_idAC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE NOO A 300
ChainResidue
APHE27
ALEU31
ALEU102
AARG104
APHE105
AALA106
AILE142
AGLY143
AVAL144
ATHR145
AMET149
ACYS177
AHOH205
AHOH224
AHOH267

Functional Information from PROSITE/UniProt
site_idPS00949
Number of Residues27
DetailsAUTOINDUCER_SYNTH_1 Autoinducer synthase family signature. YRyrvFveQlgWqLpsedekm..ErDqYD
ChainResidueDetails
ATYR22-ASP48

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PDB entries from 2025-06-18

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