7D7K
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![BU of 7d7k by Molmil](/molmil-images/mine/7d7k) | The crystal structure of SARS-CoV-2 papain-like protease in apo form | Descriptor: | 1,2-ETHANEDIOL, CAFFEINE, Non-structural protein 3, ... | Authors: | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | Deposit date: | 2020-10-04 | Release date: | 2021-04-21 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell, 12, 2021
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7D7L
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![BU of 7d7l by Molmil](/molmil-images/mine/7d7l) | The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155 | Descriptor: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, CAFFEINE, GLYCEROL, ... | Authors: | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | Deposit date: | 2020-10-04 | Release date: | 2021-04-21 | Last modified: | 2021-11-17 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell, 12, 2021
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7BR3
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![BU of 7br3 by Molmil](/molmil-images/mine/7br3) | Crystal structure of the protein 1 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R)-2,3-dihydroxypropyl dodecanoate, 4-[[(1R)-2-[5-(2-fluoranyl-3-methoxy-phenyl)-3-[[2-fluoranyl-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-bis(oxidanylidene)pyrimidin-1-yl]-1-phenyl-ethyl]amino]butanoic acid, ... | Authors: | Cheng, L, Shao, Z. | Deposit date: | 2020-03-26 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode. Nat Commun, 11, 2020
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8HIJ
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![BU of 8hij by Molmil](/molmil-images/mine/8hij) | The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex | Descriptor: | Anti-BRIL Fab heavy chain, Anti-BRIL Fab light chain, Anti-Fab nanobody, ... | Authors: | Zhang, Z, Dang, Y. | Deposit date: | 2022-11-20 | Release date: | 2022-12-21 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Molecular mechanism of substrate recognition by folate transporter SLC19A1. Cell Discov, 8, 2022
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8HII
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![BU of 8hii by Molmil](/molmil-images/mine/8hii) | The BRIL-SLC19A1/Fab/Nb ternary complex | Descriptor: | BRIL-SLC19A1 chimera, anti-BRIL Fab heavy chain, anti-BRIL Fab light chain, ... | Authors: | Zhang, Z, Dang, Y. | Deposit date: | 2022-11-20 | Release date: | 2022-12-21 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Molecular mechanism of substrate recognition by folate transporter SLC19A1. Cell Discov, 8, 2022
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8HIK
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![BU of 8hik by Molmil](/molmil-images/mine/8hik) | The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex | Descriptor: | Anti-BRIL Fab heavy chain, Anti-BRIL Fab light chain, Anti-Fab nanobody, ... | Authors: | Zhang, Z, Dang, Y. | Deposit date: | 2022-11-20 | Release date: | 2022-12-21 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Molecular mechanism of substrate recognition by folate transporter SLC19A1. Cell Discov, 8, 2022
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8FYG
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![BU of 8fyg by Molmil](/molmil-images/mine/8fyg) | Crystal structure of Hyaluronate lyase A from Cutibacterium acnes | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Hyaluronate lyase | Authors: | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | Deposit date: | 2023-01-26 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8FNX
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![BU of 8fnx by Molmil](/molmil-images/mine/8fnx) | Crystal structure of Hyaluronate lyase B from Cutibacterium acnes | Descriptor: | GLYCEROL, Hyaluronate lyase, PHOSPHATE ION | Authors: | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | Deposit date: | 2022-12-28 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8G0O
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![BU of 8g0o by Molmil](/molmil-images/mine/8g0o) | Crystal structure of Y281F mutant of Hyaluronate lyase B from Cutibacterium acnes | Descriptor: | Hyaluronate lyase | Authors: | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | Deposit date: | 2023-02-01 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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7ZEA
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![BU of 7zea by Molmil](/molmil-images/mine/7zea) | |
7ZCZ
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![BU of 7zcz by Molmil](/molmil-images/mine/7zcz) | |
7ZHI
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![BU of 7zhi by Molmil](/molmil-images/mine/7zhi) | |
7ZP2
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![BU of 7zp2 by Molmil](/molmil-images/mine/7zp2) | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-04 | Descriptor: | Aspartate carbamoyltransferase, SODIUM ION, SULFATE ION, ... | Authors: | Wang, C, Zhang, B, Groves, M.R. | Deposit date: | 2022-04-26 | Release date: | 2022-08-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
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7ZGS
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![BU of 7zgs by Molmil](/molmil-images/mine/7zgs) | |
7ZST
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![BU of 7zst by Molmil](/molmil-images/mine/7zst) | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with FLA-01 | Descriptor: | 2-azanyl-~{N}-(2-methoxyethyl)-5-phenyl-thiophene-3-carboxamide, Aspartate carbamoyltransferase, GLYCEROL, ... | Authors: | Wang, C, Zhang, B, Groves, M.R. | Deposit date: | 2022-05-08 | Release date: | 2022-08-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
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7ZID
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![BU of 7zid by Molmil](/molmil-images/mine/7zid) | |