2YHF
 
 | | 1.9 Angstrom Crystal Structure of CLEC5A | | Descriptor: | C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A | | Authors: | Watson, A.A, Lebedev, A.A, Murshudov, G.M, Vagin, A.A, Hall, B.A, O'Callaghan, C.A. | | Deposit date: | 2011-04-30 | | Release date: | 2011-05-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Flexibility of the Macrophage Dengue Virus Receptor Clec5A: Implications for Ligand Binding and Signaling.
J.Biol.Chem., 286, 2011
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5CEH
 | | Structure of histone lysine demethylase KDM5A in complex with selective inhibitor | | Descriptor: | 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, NICKEL (II) ION, ... | | Authors: | Kiefer, J.R, Vinogradova, M. | | Deposit date: | 2015-07-06 | | Release date: | 2016-05-18 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.14 Å) | | Cite: | An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Nat.Chem.Biol., 12, 2016
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5CAJ
 | | Crystal structure of E. coli YaaA, a member of the DUF328/UPF0246 family | | Descriptor: | BENZAMIDINE, CHLORIDE ION, UPF0246 protein YaaA | | Authors: | Prahlad, J, Lin, J, Wilson, M.A. | | Deposit date: | 2015-06-29 | | Release date: | 2016-02-24 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The DUF328 family member YaaA is a DNA-binding protein with a novel fold.
J.Biol.Chem., 295, 2020
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5D0N
 | | Crystal structure of maize PDRP bound with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Pyruvate, ... | | Authors: | Jiang, L, Chen, Z. | | Deposit date: | 2015-08-03 | | Release date: | 2016-02-24 | | Last modified: | 2016-03-09 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Basis of Reversible Phosphorylation by Maize Pyruvate Orthophosphate Dikinase Regulatory Protein
Plant Physiol., 170, 2016
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3W53
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3FPN
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2MJ8
 | | Solution structure of CDYL2 chromodomain | | Descriptor: | Chromodomain Y-like protein 2 | | Authors: | Qin, S, Houliston, S, Arrowsmith, C.H, Edwards, A.M, Wu, H, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-28 | | Release date: | 2014-04-23 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
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4I1L
 | | Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function | | Descriptor: | ACETATE ION, Forkhead box protein P3, MAGNESIUM ION, ... | | Authors: | Song, X.M, Greene, M.I, Zhou, Z.C. | | Deposit date: | 2012-11-21 | | Release date: | 2012-12-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.
Cell Rep, 1, 2012
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7XOE
 | | Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Prefusion state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide | | Authors: | Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J. | | Deposit date: | 2022-05-01 | | Release date: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
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7XOG
 | | Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Postfusion state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide, ... | | Authors: | Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J. | | Deposit date: | 2022-05-01 | | Release date: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
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8OKX
 | | Structure of cGAS in complex with SPSB3-ELOBC | | Descriptor: | Cyclic GMP-AMP synthase, Elongin-B, Elongin-C, ... | | Authors: | Xu, P.B, Ablasser, A. | | Deposit date: | 2023-03-29 | | Release date: | 2024-02-14 | | Last modified: | 2024-04-10 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Nature, 627, 2024
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8OL1
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8JYS
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8K11
 | | SID1 transmembrane family member 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2 | | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | | Deposit date: | 2023-07-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
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8K12
 | | SID1 transmembrane family member 2 | | Descriptor: | SID1 transmembrane family member 2 | | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | | Deposit date: | 2023-07-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
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8K1B
 | | SID1 transmembrane family member 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1 | | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | | Deposit date: | 2023-07-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
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8K10
 | | SID1 transmembrane family member 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2 | | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | | Deposit date: | 2023-07-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
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8K13
 | | SID1 transmembrane family member 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1 | | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | | Deposit date: | 2023-07-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
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8K1D
 | | SID1 transmembrane family member 1 | | Descriptor: | SID1 transmembrane family member 1 | | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | | Deposit date: | 2023-07-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity.
Cell Res., 34, 2024
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4NW2
 | | Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229 | | Descriptor: | Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... | | Authors: | Qin, S, Tempel, W, Xu, C, El Bakkouri, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-05 | | Release date: | 2014-01-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
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4O45
 | | WDR5 in complex with influenza NS1 C-terminal tail | | Descriptor: | Nonstructural protein 1, UNKNOWN ATOM OR ION, WD repeat-containing protein 5 | | Authors: | Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-18 | | Release date: | 2014-04-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
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4O42
 | | Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229 | | Descriptor: | Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... | | Authors: | Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-18 | | Release date: | 2014-04-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
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8R8A
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8R8C
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2HIW
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