7XOG

Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Postfusion state)

Summary for 7XOG

• Entry DOI: 10.2210/pdb7xog/pdb
• EMDB information: 33347
• Descriptor: Spike glycoprotein,peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: spike, mrna vaccine, sars-cov-2, s clycoprotein, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus; More
• Total number of polymer chains: 3
• Total formula weight: 439731.57

Authors

Wu, Z.,Yu, Z.,Tan, S.,Lu, J.,Lu, G.,Lin, J. (deposition date: 2022-05-01, release date: 2024-03-20)

• Primary citation: Tan, S.,Zhao, J.,Hu, X.,Li, Y.,Wu, Z.,Lu, G.,Yu, Z.,Du, B.,Liu, Y.,Li, L.,Chen, Y.,Li, Y.,Yao, Y.,Zhang, X.,Rao, J.,Gao, G.,Peng, Y.,Liu, H.,Yuan, Z.,Liu, J.,Wang, Q.,Hu, H.,Gao, X.,Zhou, H.,Yu, H.,Xu, Y.,Yu, W.,Feng, L.,Wang, M.,Shan, C.,Lu, J.,Lin, J.; Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.; Sci Bull (Beijing), 68:3192-3206, 2023; PubMed: 37993332; DOI: 10.1016/j.scib.2023.11.024

Experimental method

ELECTRON MICROSCOPY (3.5 Å)