4O45

WDR5 in complex with influenza NS1 C-terminal tail

Summary for 4O45

• Entry DOI: 10.2210/pdb4o45/pdb
• Descriptor: WD repeat-containing protein 5, Nonstructural protein 1, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: viral, structural genomics, structural genomics consortium, sgc, transcription-rna binding protein complex, transcription/rna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P61964; Host nucleus: Q9YP60
• Total number of polymer chains: 2
• Total formula weight: 36082.11

Authors

Qin, S.,Xu, C.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2013-12-18, release date: 2014-04-23, Last modification date: 2024-04-03)

• Primary citation: Qin, S.,Liu, Y.,Tempel, W.,Eram, M.S.,Bian, C.,Liu, K.,Senisterra, G.,Crombet, L.,Vedadi, M.,Min, J.; Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.; Nat Commun, 5:3952-3952, 2014; PubMed: 24853335; DOI: 10.1038/ncomms4952

Experimental method

X-RAY DIFFRACTION (1.87 Å)