4I1L

Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

Summary for 4I1L

Entry DOI	10.2210/pdb4i1l/pdb
Related	3HSX
Descriptor	Forkhead box protein P3, SULFATE ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	foxp3, dimerization, complex ensemble, stability, regulatory activity, acetyation, dna-binding, metal-binding, nucleus, transcription, zinc-finger, transcription regulator
Biological source	Mus musculus (mouse)
Cellular location	Nucleus (Potential): Q99JB6
Total number of polymer chains	1
Total formula weight	10758.09
Authors	Song, X.M.,Greene, M.I.,Zhou, Z.C. (deposition date: 2012-11-21, release date: 2012-12-05, Last modification date: 2024-03-20)
Primary citation	Song, X.,Li, B.,Xiao, Y.,Chen, C.,Wang, Q.,Liu, Y.,Berezov, A.,Xu, C.,Gao, Y.,Li, Z.,Wu, S.L.,Cai, Z.,Zhang, H.,Karger, B.L.,Hancock, W.W.,Wells, A.D.,Zhou, Z.,Greene, M.I. Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function. Cell Rep, 1:665-675, 2012 Cited by PubMed: 22813742 DOI: 10.1016/j.celrep.2012.04.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation