8JYS

SARS-CoV-2 Spike RBD (dimer) in complex with two 2S-1244 nanobodies

Summary for 8JYS

Entry DOI	10.2210/pdb8jys/pdb
EMDB information	36730
Descriptor	IBT-CoV144 nanobody, Spike protein S1 (2 entities in total)
Functional Keywords	spike, nanobody, dimer, local, viral protein
Biological source	Camelus bactrianus More
Total number of polymer chains	4
Total formula weight	75416.53
Authors	Yang, Y.,Zhang, C.H. (deposition date: 2023-07-03, release date: 2024-06-12)
Primary citation	Yang, Y.,Zhang, J.,Zhang, S.,Zhang, C.,Shen, C.,Song, S.,Wang, Y.,Peng, Y.,Gong, X.,Dai, J.,Xie, C.,Khrustaleva, T.A.,Khrustalev, V.V.,Huo, Y.,Lu, D.,Yao, D.,Zhao, J.,Liu, Y.,Lu, H. A novel nanobody broadly neutralizes SARS-CoV-2 via induction of spike trimer dimers conformation Exploration, :20230086-, 2023 Cited by DOI: 10.1002/EXP.20230086 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.5 Å)

Structure validation