5ZIA
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5ZUV
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![BU of 5zuv by Molmil](/molmil-images/mine/5zuv) | Crystal Structure of the Human Coronavirus 229E HR1 motif in complex with pan-CoVs inhibitor EK1 | Descriptor: | CHLORIDE ION, Spike glycoprotein,Spike glycoprotein,inhibitor EK1 | Authors: | Yan, L, Yang, B, Wilson, I.A. | Deposit date: | 2018-05-08 | Release date: | 2019-04-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5, 2019
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5ZVM
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![BU of 5zvm by Molmil](/molmil-images/mine/5zvm) | |
4K3H
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![BU of 4k3h by Molmil](/molmil-images/mine/4k3h) | Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green | Descriptor: | 4-{bis[4-(dimethylamino)phenyl]methyl}phenol, GLYCEROL, Immunoglobulin lambda variable domain L5(L89S), ... | Authors: | Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A. | Deposit date: | 2013-04-10 | Release date: | 2013-10-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces. J.Mol.Biol., 425, 2013
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4K3D
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![BU of 4k3d by Molmil](/molmil-images/mine/4k3d) | Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3 | Descriptor: | BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ... | Authors: | Ekiert, D.C, Wang, F, Wilson, I.A. | Deposit date: | 2013-04-10 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Reshaping antibody diversity. Cell(Cambridge,Mass.), 153, 2013
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4K3G
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![BU of 4k3g by Molmil](/molmil-images/mine/4k3g) | |
2VAA
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![BU of 2vaa by Molmil](/molmil-images/mine/2vaa) | |
2VAB
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![BU of 2vab by Molmil](/molmil-images/mine/2vab) | |
8TFR
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![BU of 8tfr by Molmil](/molmil-images/mine/8tfr) | Apo Fab from C10-S66K antibody | Descriptor: | Heavy chain from Fab of C10_S66K antibody, Immunoglobulin G-binding protein G, Light chain from Fab of C10_S66K antibody | Authors: | Pholcharee, T, Wilson, I.A. | Deposit date: | 2023-07-11 | Release date: | 2023-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023
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8TFP
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![BU of 8tfp by Molmil](/molmil-images/mine/8tfp) | Fab from C10-S66K antibody in complex with carfentanil | Descriptor: | Carfentanil, Heavy chain of Fab from C10-S66K antibody, Light chain of Fab from C10-S66K antibody | Authors: | Pholcharee, T, Wilson, I.A. | Deposit date: | 2023-07-11 | Release date: | 2023-08-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023
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8TFQ
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![BU of 8tfq by Molmil](/molmil-images/mine/8tfq) | Fab from C10-S66K antibody in complex with fentanyl | Descriptor: | Heavy chain from Fab of C10_S66K antibody, Light chain from Fab of C10_S66K antibody, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide | Authors: | Pholcharee, T, Wilson, I.A. | Deposit date: | 2023-07-11 | Release date: | 2023-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14, 2023
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6WOS
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6WIY
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![BU of 6wiy by Molmil](/molmil-images/mine/6wiy) | Crystal structure of Fab 54-1G05 | Descriptor: | Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, GLYCEROL | Authors: | Wu, N.C, Wilson, I.A. | Deposit date: | 2020-04-11 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
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6X1T
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![BU of 6x1t by Molmil](/molmil-images/mine/6x1t) | Structure of pHis Fab (SC50-3) in complex with pHis mimetic peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kalagiri, R, Stanfield, R.L, Wilson, I.A, Hunter, T. | Deposit date: | 2020-05-19 | Release date: | 2021-02-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 118, 2021
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6WIZ
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![BU of 6wiz by Molmil](/molmil-images/mine/6wiz) | Crystal structure of Fab 54-1G05 bound to H1 influenza hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, ... | Authors: | Wu, N.C, Wilson, I.A. | Deposit date: | 2020-04-11 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
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6X1W
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![BU of 6x1w by Molmil](/molmil-images/mine/6x1w) | Structure of pHis Fab (SC56-2) in complex with pHis mimetic peptide | Descriptor: | ACLYana-3-pTza peptide, SC56-2 Heavy chain, SC56-2 Light chain | Authors: | Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T. | Deposit date: | 2020-05-19 | Release date: | 2021-02-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 118, 2021
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6WOR
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6X1U
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![BU of 6x1u by Molmil](/molmil-images/mine/6x1u) | Structure of pHis Fab (SC39-4) in complex with pHis mimetic peptide | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACLYana-3-pTza peptide, ... | Authors: | Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T. | Deposit date: | 2020-05-19 | Release date: | 2021-02-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.641 Å) | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 118, 2021
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6X1S
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![BU of 6x1s by Molmil](/molmil-images/mine/6x1s) | Structure of pHis Fab (SC1-1) in complex with pHis mimetic peptide | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, NM23-1-pTza peptide, SC1-1 Heavy chain, ... | Authors: | Kalagiri, R, Stanfield, R.L, Wilson, I.A, Hunter, T. | Deposit date: | 2020-05-19 | Release date: | 2021-02-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 118, 2021
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6XC4
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![BU of 6xc4 by Molmil](/molmil-images/mine/6xc4) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 heavy chain, CC12.3 light chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.341 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
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6XC3
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![BU of 6xc3 by Molmil](/molmil-images/mine/6xc3) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.1 and CR3022 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.698 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
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6XC7
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![BU of 6xc7 by Molmil](/molmil-images/mine/6xc7) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.3 and CR3022 | Descriptor: | CC12.3 heavy chain, CC12.3 light chain, CR3022 heavy chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.883 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
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6XC2
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![BU of 6xc2 by Molmil](/molmil-images/mine/6xc2) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... | Authors: | Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. | Deposit date: | 2020-06-08 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.112 Å) | Cite: | Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
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6DCV
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![BU of 6dcv by Molmil](/molmil-images/mine/6dcv) | Crystal structure of human anti-tau antibody CBTAU-27.1 | Descriptor: | GLYCEROL, Light chain of CBTAU27.1 Fab, heavy chain of CBTAU-27.1 Fab | Authors: | Zhu, X, Zhang, H, Wilson, I.A. | Deposit date: | 2018-05-08 | Release date: | 2018-06-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018
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6DID
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![BU of 6did by Molmil](/molmil-images/mine/6did) | HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B. | Deposit date: | 2018-05-23 | Release date: | 2018-09-05 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.71 Å) | Cite: | Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity, 49, 2018
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