Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.3 and CR3022

Summary for 6XC7

Related6XC2 6XC3 6XC4
DescriptorSpike protein S1, CR3022 heavy chain, CR3022 light chain, ... (6 entities in total)
Functional Keywordsantibody, sars-cov-2, coronavirus, spike, immune system, immune system-viral protein complex, immune system/viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains5
Total molecular weight121323.39
Yuan, M.,Liu, H.,Wu, N.C.,Zhu, X.,Wilson, I.A. (deposition date: 2020-06-08, release date: 2020-07-08, Last modification date: 2020-07-29)
Primary citation
Yuan, M.,Liu, H.,Wu, N.C.,Lee, C.D.,Zhu, X.,Zhao, F.,Huang, D.,Yu, W.,Hua, Y.,Tien, H.,Rogers, T.F.,Landais, E.,Sok, D.,Jardine, J.G.,Burton, D.R.,Wilson, I.A.
Structural basis of a public antibody response to SARS-CoV-2.
Biorxiv, 2020
PubMed: 32577642 (PDB entries with the same primary citation)
DOI: 10.1101/2020.06.08.141267
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2607 0.2% 3.6% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-12