6XC7

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.3 and CR3022

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	231	26095.3	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
2	H	CR3022 heavy chain	polymer	222	23455.4	1		Homo sapiens
3	L	CR3022 light chain	polymer	221	24377.0	1		Homo sapiens
4	C	CC12.3 heavy chain	polymer	220	23377.2	1		Homo sapiens
5	D	CC12.3 light chain	polymer	215	23432.0	1		Homo sapiens
6	B	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)

Sequence modifications

A: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	120736.8
Branched	Number of molecules	1
	Total formula weight	586.5
All*	Total formula weight	121323.4

*Water molecules are not included.