8UNH
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![BU of 8unh by Molmil](/molmil-images/mine/8unh) | Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ... | Authors: | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | Deposit date: | 2023-10-19 | Release date: | 2023-12-13 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
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8UNF
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![BU of 8unf by Molmil](/molmil-images/mine/8unf) | Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ... | Authors: | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | Deposit date: | 2023-10-18 | Release date: | 2023-12-13 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
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6F4E
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![BU of 6f4e by Molmil](/molmil-images/mine/6f4e) | Crystal structure of the zinc-free catalytic domain of botulinum neurotoxin X | Descriptor: | Catalytic domain of botulinum neurotoxin X, DI(HYDROXYETHYL)ETHER | Authors: | Masuyer, G, Henriksson, L, Kosenina, S, Zhang, S, Barkho, S, Shen, Y, Dong, M, Stenmark, P. | Deposit date: | 2017-11-29 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity. Sci Rep, 8, 2018
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6F47
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![BU of 6f47 by Molmil](/molmil-images/mine/6f47) | Crystal structure of the catalytic domain of botulinum neurotoxin X | Descriptor: | Catalytic domain of botulinum neurotoxin X, ZINC ION | Authors: | Masuyer, G, Henriksson, L, Kosenina, S, Zhang, S, Barkho, S, Shen, Y, Dong, M, Stenmark, P. | Deposit date: | 2017-11-29 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity. Sci Rep, 8, 2018
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7YE6
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![BU of 7ye6 by Molmil](/molmil-images/mine/7ye6) | BAM-EspP complex structure with BamA-N427C/EspP-R1297C mutations in nanodisc | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly. Nature, 617, 2023
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7YE4
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![BU of 7ye4 by Molmil](/molmil-images/mine/7ye4) | BAM-EspP complex structure with BamA-G431C and G781C/EspP-N1293C and A1043C mutations in nanodisc | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly. Nature, 617, 2023
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7NFX
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![BU of 7nfx by Molmil](/molmil-images/mine/7nfx) | Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Lee, J.H, Shan, S, Ban, N. | Deposit date: | 2021-02-08 | Release date: | 2021-06-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. Sci Adv, 7, 2021
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6PNJ
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![BU of 6pnj by Molmil](/molmil-images/mine/6pnj) | Structure of Photosystem I Acclimated to Far-red Light | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | Authors: | Gisriel, C.J, Shen, G, Kurashov, V, Ho, M, Zhang, S, Williams, D, Golbeck, J.H, Fromme, P, Bryant, D.A. | Deposit date: | 2019-07-02 | Release date: | 2020-02-12 | Last modified: | 2020-02-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The structure of Photosystem I acclimated to far-red light illuminates an ecologically important acclimation process in photosynthesis Sci Adv, 6, 2020
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6YQY
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![BU of 6yqy by Molmil](/molmil-images/mine/6yqy) | Crystal structure of sTIM11noCys, a de novo designed TIM barrel | Descriptor: | de novo designed TIM barrel sTIM11noCys | Authors: | Romero-Romero, S, Wiese, G.J, Kordes, S, Shanmugaratnam, S, Fernandez-Velasco, D.A, Hocker, B. | Deposit date: | 2020-04-18 | Release date: | 2021-07-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.876 Å) | Cite: | The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021
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6YQX
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![BU of 6yqx by Molmil](/molmil-images/mine/6yqx) | Crystal structure of DeNovoTIM13, a de novo designed TIM barrel | Descriptor: | CHLORIDE ION, GLYCEROL, de novo designed TIM barrel DeNovoTIM13 | Authors: | Romero-Romero, S, Kordes, S, Shanmugaratnam, S, Fernandez-Velasco, D.A, Hocker, B. | Deposit date: | 2020-04-18 | Release date: | 2021-07-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.638 Å) | Cite: | The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021
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7RHA
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![BU of 7rha by Molmil](/molmil-images/mine/7rha) | A new fluorescent protein darkmRuby at pH 5.0 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, SULFATE ION, ... | Authors: | Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J. | Deposit date: | 2021-07-16 | Release date: | 2022-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a new fluorescent protein darkmRuby at pH 5.0 To Be Published
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7RHB
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7RHD
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![BU of 7rhd by Molmil](/molmil-images/mine/7rhd) | darkmRuby M94T/F96Y mutant at pH 7.5 | Descriptor: | 1,2-ETHANEDIOL, darkmRuby M94T/F96Y mutant | Authors: | Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J. | Deposit date: | 2021-07-16 | Release date: | 2022-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Long-range Interaction Affects Brightness and pH Stability of a Dark Fluorescent Protein To Be Published
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7RHC
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![BU of 7rhc by Molmil](/molmil-images/mine/7rhc) | A new fluorescent protein darkmRuby at pH 9.0 | Descriptor: | 1,2-ETHANEDIOL, darkmRuby | Authors: | Huang, M, Ng, H.L, Zhang, S, Deng, M, Chu, J. | Deposit date: | 2021-07-16 | Release date: | 2022-07-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Long-range Interaction Affects Brightness and pH Stability of a Dark Fluorescent Protein To Be Published
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3HH0
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![BU of 3hh0 by Molmil](/molmil-images/mine/3hh0) | Crystal structure of a transcriptional regulator, MerR family from Bacillus cereus | Descriptor: | Transcriptional regulator, MerR family | Authors: | Palani, K, Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-05-14 | Release date: | 2009-05-26 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Crystal structure of a transcriptional regulator, MerR family from Bacillus cereus To be Published
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6P3Q
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![BU of 6p3q by Molmil](/molmil-images/mine/6p3q) | Calpain-5 (CAPN5) Protease Core (PC) | Descriptor: | Calpain-5 | Authors: | Velez, G, Sun, Y.J, Khan, S, Yang, J, Koster, H.J, Lokesh, G, Mahajan, V. | Deposit date: | 2019-05-24 | Release date: | 2020-02-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants. Cell Rep, 30, 2020
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3SSZ
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![BU of 3ssz by Molmil](/molmil-images/mine/3ssz) | The crystal structure of Mandelate racemase/muconate lactonizing enzyme from Rhodobacteraceae bacterium | Descriptor: | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein, SULFATE ION | Authors: | Zhang, Z, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-07-08 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.392 Å) | Cite: | The crystal structure of Mandelate racemase/muconate lactonizing enzyme from Rhodobacteraceae bacterium To be Published
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3KCM
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3T4W
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![BU of 3t4w by Molmil](/molmil-images/mine/3t4w) | The crystal structure of mandelate racemase/muconate lactonizing enzyme from Sulfitobacter sp | Descriptor: | Mandelate racemase/muconate lactonizing enzyme family protein | Authors: | Zhang, Z, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-07-26 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.522 Å) | Cite: | The crystal structure of mandelate racemase/muconate lactonizing enzyme from Sulfitobacter sp To be Published
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3KXW
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3OMH
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![BU of 3omh by Molmil](/molmil-images/mine/3omh) | Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide | Descriptor: | Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y. | Deposit date: | 2010-08-26 | Release date: | 2011-06-29 | Last modified: | 2011-09-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate. J.Biol.Chem., 286, 2011
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8RIJ
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![BU of 8rij by Molmil](/molmil-images/mine/8rij) | Discovery of the first orally bioavailable ADAMTS7 inhibitor BAY-9835 | Descriptor: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Schafer, M, Meibom, D, Wasnaire, P, Beyer, K, Broehl, A, Cancho-Grande, Y, Elowe, N, Henninger, K, Johannes, S, Jungmann, N, Krainz, T, Lindner, N, Maassen, S, MacDonald, B, Menshykau, D, Mittendorf, J, Sanchez, G, Stefan, E, Torge, A, Xing, Y, Zubov, D. | Deposit date: | 2023-12-18 | Release date: | 2024-02-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor. J.Med.Chem., 67, 2024
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3KZB
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3KCN
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3TG9
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![BU of 3tg9 by Molmil](/molmil-images/mine/3tg9) | The crystal structure of penicillin binding protein from Bacillus halodurans | Descriptor: | Penicillin-binding protein | Authors: | Zhang, Z, Satyanarayana, L, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-08-17 | Release date: | 2011-08-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of penicillin binding protein from Bacillus halodurans To be Published
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