6P3Q
Calpain-5 (CAPN5) Protease Core (PC)
Summary for 6P3Q
Entry DOI | 10.2210/pdb6p3q/pdb |
Descriptor | Calpain-5 (1 entity in total) |
Functional Keywords | cystein protease, peptide binding protein, calcium binding protein, protease domain, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 82733.20 |
Authors | Velez, G.,Sun, Y.J.,Khan, S.,Yang, J.,Koster, H.J.,Lokesh, G.,Mahajan, V. (deposition date: 2019-05-24, release date: 2020-02-05, Last modification date: 2024-04-03) |
Primary citation | Velez, G.,Sun, Y.J.,Khan, S.,Yang, J.,Herrmann, J.,Chemudupati, T.,MacLaren, R.E.,Gakhar, L.,Wakatsuki, S.,Bassuk, A.G.,Mahajan, V.B. Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants. Cell Rep, 30:881-892.e5, 2020 Cited by PubMed: 31968260DOI: 10.1016/j.celrep.2019.12.077 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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