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7RM0
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BU of 7rm0 by Molmil
Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPG
Descriptor: 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, peptide from Circumsporozoite protein variant VK247
Authors:Kucharska, I, Ivanochko, D, Julien, J.P.
Deposit date:2021-07-26
Release date:2022-01-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats.
Elife, 11, 2022
7RM3
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BU of 7rm3 by Molmil
Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPGANGAGGQAA
Descriptor: 2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, ACETATE ION, ...
Authors:Kucharska, I, Ivanochko, D, Julien, J.P.
Deposit date:2021-07-26
Release date:2022-01-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats.
Elife, 11, 2022
7RLW
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BU of 7rlw by Molmil
Antibody 2F2 in complex with P. vivax CSP peptide GDRAAGQPAGDRAAGQPA
Descriptor: 2F2 Fab heavy chain, 2F2 Fab light chain, PvCSPvk210 peptide from Circumsporozoite protein
Authors:Kucharska, I, Julien, J.P.
Deposit date:2021-07-26
Release date:2022-01-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats.
Elife, 11, 2022
6PHF
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BU of 6phf by Molmil
Pfs25 in complex with the human transmission blocking antibody 2587
Descriptor: 25 kDa ookinete surface antigen, 2587 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHH
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BU of 6phh by Molmil
Unliganded human transmission blocking antibody 2544
Descriptor: 2544 Antibody Fab, Heavy Chain, Light Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHC
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BU of 6phc by Molmil
Pfs25 in complex with the human transmission blocking antibody 2544
Descriptor: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHB
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BU of 6phb by Molmil
Pfs25 in complex with the human transmission blocking antibody 2530
Descriptor: 1,2-ETHANEDIOL, 25 kDa ookinete surface antigen, 2530 Antibody Fab, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHG
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BU of 6phg by Molmil
Predicted germline variant of human transmission blocking antibody 2544
Descriptor: GLYCEROL, Germline 2544 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHD
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BU of 6phd by Molmil
Pfs25 in complex with the human transmission blocking antibody 2586
Descriptor: 25 kDa ookinete surface antigen, 2586 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6AZX
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BU of 6azx by Molmil
Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody
Descriptor: 663 antibody, heavy chain, light chain
Authors:Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
Deposit date:2017-09-13
Release date:2017-12-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
6B0W
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BU of 6b0w by Molmil
Crystal structure of the anti-circumsporozoite protein 1710 antibody
Descriptor: 1710 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
Deposit date:2017-09-15
Release date:2017-11-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
6AZZ
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BU of 6azz by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190
Descriptor: 1190 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0E
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BU of 6b0e by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260
Descriptor: 1260 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6AZM
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BU of 6azm by Molmil
Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer
Descriptor: 580 germline antibody, heavy chain, light chain, ...
Authors:Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
Deposit date:2017-09-11
Release date:2017-12-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
6B0G
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BU of 6b0g by Molmil
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
Descriptor: 1245 Antibody, Heavy Chain, Light Chain, ...
Authors:McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P.
Deposit date:2017-09-14
Release date:2017-11-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
6B0S
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BU of 6b0s by Molmil
Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody
Descriptor: 1710 antibody, heavy chain, light chain, ...
Authors:Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
Deposit date:2017-09-15
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
8DNN
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BU of 8dnn by Molmil
Crystal structure of neutralizing antibody 80 in complex with SARS-CoV-2 receptor binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 80 FAB HEAVY CHAIN, 80 FAB LIGHT CHAIN, ...
Authors:Muthuraman, K, Kucharska, I, Ivanochko, D, Julien, J.P.
Deposit date:2022-07-11
Release date:2023-05-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo.
Sci Transl Med, 15, 2023
8FG0
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BU of 8fg0 by Molmil
Crystal structure of the 3764 Fab in complex with the C-terminal PfCSP linker, PfCSP281-294.
Descriptor: 3764 Fab Heavy chain, 3764 Fab Light chain, Circumsporozoite protein
Authors:Burn Aschner, C, Julien, J.P.
Deposit date:2022-12-11
Release date:2023-05-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies.
Embo Mol Med, 15, 2023
8F9E
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BU of 8f9e by Molmil
Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein KQPA peptide
Descriptor: Circumsporozoite protein KQPA peptide, Ky15.2 Antibody, heavy chain, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-23
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8FAT
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BU of 8fat by Molmil
Crystal structure of Ky224 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: Circumsporozoite protein NPDP peptide, Ky224 Antibody, heavy chain, ...
Authors:Kassardjian, A, Thai, E, Julien, J.P.
Deposit date:2022-11-28
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8F95
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BU of 8f95 by Molmil
Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein DND peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein DND peptide, Ky15.2 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-23
Release date:2023-11-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8F9T
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BU of 8f9t by Molmil
Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.2 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-24
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8F9W
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BU of 8f9w by Molmil
Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.8 Antibody, ...
Authors:Thai, E, Prieto, K, Julien, J.P.
Deposit date:2022-11-24
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8F9S
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BU of 8f9s by Molmil
Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NDN peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NDN peptide, Ky15.2 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-24
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8FAN
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BU of 8fan by Molmil
Crystal structure of Ky15.1 Fab in complex with circumsporozoite protein KQPA peptide
Descriptor: Circumsporozoite protein KQPA peptide, Ky15.1 Antibody, heavy chain, ...
Authors:Burn Aschner, C, Thai, E, Julien, J.P.
Deposit date:2022-11-28
Release date:2023-11-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023

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