7RM0

Antibody 2E10.E9 in complex with P. vivax CSP peptide ANGAGNQPGANGAGNQPG

Summary for 7RM0

Entry DOI	10.2210/pdb7rm0/pdb
Descriptor	2E10.E9 Fab heavy chain, 2E10.E9 Fab light chain, peptide from Circumsporozoite protein variant VK247, ... (4 entities in total)
Functional Keywords	antibody, malaria, plasmodium vivax, circumsporozoite protein, antimicrobial protein
Biological source	Mus musculus (mouse) More
Total number of polymer chains	12
Total formula weight	198240.03
Authors	Kucharska, I.,Ivanochko, D.,Julien, J.P. (deposition date: 2021-07-26, release date: 2022-01-26, Last modification date: 2023-10-18)
Primary citation	Kucharska, I.,Hossain, L.,Ivanochko, D.,Yang, Q.,Rubinstein, J.L.,Pomes, R.,Julien, J.P. Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats. Elife, 11:-, 2022 Cited by PubMed: 35023832 DOI: 10.7554/eLife.72908 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation