8YET
| Cryo EM structure of human phosphate channel XPR1 in complex with IP6 | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-23 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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9IWS
| Cryo EM structure of human phosphate channel XPR1 in complex with IP7 | Descriptor: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-07-25 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YEX
| Cryo EM structure of human phosphate channel XPR1 at apo state | Descriptor: | Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-23 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YF4
| Cryo EM structure of human phosphate channel XPR1 at open and inward-facing state | Descriptor: | CHOLESTEROL HEMISUCCINATE, Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-24 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFD
| Cryo EM structure of human phosphate channel XPR1 at open state | Descriptor: | Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-24 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFU
| Cryo EM structure of human phosphate channel XPR1 at intermediate state | Descriptor: | Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-25 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (4.59 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFX
| Cryo EM structure of human phosphate channel XPR1 at inward-facing state | Descriptor: | Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-25 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8YFW
| Cryo EM structure of human phosphate channel XPR1 at intermediate state | Descriptor: | Solute carrier family 53 member 1 | Authors: | Lu, Y, Yue, C, Zhang, L, Yao, D, Yu, Y, Cao, Y. | Deposit date: | 2024-02-25 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1. Science, 2024
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8ZLE
| hAE3NTD2TMD with PT5,CLR, and Y01 | Descriptor: | CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, ... | Authors: | Jian, L, Zhang, Q, Yao, D, Wang, Q, Xia, Y, Qin, A, Cao, Y. | Deposit date: | 2024-05-19 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | The structural insight into the functional modulation of human anion exchanger 3. Nat Commun, 15, 2024
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8J8Q
| Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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8J8P
| Structure of the four-component Paf1 complex from Saccharomyces eubayanus | Descriptor: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | Authors: | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-05-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus . Int J Mol Sci, 24, 2023
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6EBA
| Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Unoccupied Conformation | Descriptor: | Major facilitator family transporter | Authors: | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | Deposit date: | 2018-08-06 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.812 Å) | Cite: | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster Sci Bull (Beijing), 64, 2019
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6E9C
| Selenomethionine Derivative Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster | Descriptor: | Major facilitator family transporter | Authors: | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | Deposit date: | 2018-07-31 | Release date: | 2019-08-14 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster Sci Bull (Beijing), 64, 2019
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6E8J
| Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Occupied Conformation | Descriptor: | Major facilitator family transporter | Authors: | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | Deposit date: | 2018-07-30 | Release date: | 2019-08-14 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (3.091 Å) | Cite: | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster Sci Bull (Beijing), 64, 2019
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7WVB
| Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state | Descriptor: | Fructose-1,6-bisphosphatase 1 | Authors: | Chen, Y, Zhang, J, Li, C, Cao, Y. | Deposit date: | 2022-02-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state To Be Published
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6LGW
| Structure of Rabies virus glycoprotein in complex with neutralizing antibody 523-11 at acidic pH | Descriptor: | Glycoprotein, scFv 523-11 | Authors: | Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W. | Deposit date: | 2019-12-06 | Release date: | 2020-02-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9037 Å) | Cite: | Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody. Cell Host Microbe, 27, 2020
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6LGX
| Structure of Rabies virus glycoprotein at basic pH | Descriptor: | Glycoprotein,Glycoprotein,Glycoprotein | Authors: | Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W. | Deposit date: | 2019-12-06 | Release date: | 2020-02-19 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.097 Å) | Cite: | Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody. Cell Host Microbe, 27, 2020
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6KXW
| Crystal structure of human aquaporin AQP7 in bound to glycerol | Descriptor: | Aquaporin-7, GLYCEROL | Authors: | Zhang, L, Yao, D, Zhou, F, Zhang, Q, Zhou, L, Cao, Y. | Deposit date: | 2019-09-13 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | The structural basis for glycerol permeation by human AQP7 Sci Bull (Beijing), 66, 2020
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6L8R
| membrane-bound PD-L1-CD | Descriptor: | Programmed cell death 1 ligand 1 | Authors: | Maorong, W, Cao, Y, Bin, W, Bo, O. | Deposit date: | 2019-11-07 | Release date: | 2020-11-11 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain. Nat Commun, 12, 2021
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7WVK
| Crystal structure of human WDR5 in complex with compound 19 | Descriptor: | 1,2-ETHANEDIOL, 1-[2,5-bis(chloranyl)phenyl]sulfonylbenzimidazole, GLYCEROL, ... | Authors: | Han, Q.L, Zhang, X.L, Wang, L, Ren, P.X, Cao, Y, Li, K, Bai, F. | Deposit date: | 2022-02-10 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol.Sin., 44, 2023
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5JDB
| Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens | Descriptor: | Outer capsid protein VP4 | Authors: | Sun, X, Guo, N, Li, D, Zhou, Y, Jin, M, Xie, G, Pang, L, Zhang, Q, Cao, Y, Duan, Z. | Deposit date: | 2016-04-16 | Release date: | 2016-07-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens. Virology, 495, 2016
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3EB4
| Voltage-dependent K+ channel beta subunit (I211R) in complex with cortisone | Descriptor: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2 | Authors: | Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M. | Deposit date: | 2008-08-26 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4, 2008
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3EB3
| Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone | Descriptor: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2 | Authors: | Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M. | Deposit date: | 2008-08-26 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4, 2008
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3EAU
| Voltage-dependent K+ channel beta subunit in complex with cortisone | Descriptor: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2 | Authors: | Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M. | Deposit date: | 2008-08-26 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4, 2008
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6LSA
| Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | Authors: | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | Deposit date: | 2020-01-17 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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