6L8R

membrane-bound PD-L1-CD

Summary for 6L8R

• Entry DOI: 10.2210/pdb6l8r/pdb
• NMR Information: BMRB: 36293
• Descriptor: Programmed cell death 1 ligand 1 (1 entity in total)
• Functional Keywords: pd-l1, membrane-bound, cytoplasmic domain, stability, immunosuppressant
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 3797.37

Authors

Maorong, W.,Cao, Y.,Bin, W.,Bo, O. (deposition date: 2019-11-07, release date: 2020-11-11, Last modification date: 2023-06-14)

• Primary citation: Wen, M.,Cao, Y.,Wu, B.,Xiao, T.,Cao, R.,Wang, Q.,Liu, X.,Xue, H.,Yu, Y.,Lin, J.,Xu, C.,Xu, J.,OuYang, B.; PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.; Nat Commun, 12:5106-5106, 2021; PubMed: 34429434; DOI: 10.1038/s41467-021-25416-7

Experimental method

SOLUTION NMR