7WH1
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![BU of 7wh1 by Molmil](/molmil-images/mine/7wh1) | structure of C elegans BCMO-2 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7WH0
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![BU of 7wh0 by Molmil](/molmil-images/mine/7wh0) | structure of C elegans BCMO-1 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7X8J
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7X8K
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![BU of 7x8k by Molmil](/molmil-images/mine/7x8k) | Arabidopsis GDP-D-mannose pyrophosphorylase (VTC1) structure (product-bound) | Descriptor: | CITRATE ANION, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, Mannose-1-phosphate guanylyltransferase 1, ... | Authors: | Zhao, S, Zhang, C, Liu, L. | Deposit date: | 2022-03-13 | Release date: | 2022-05-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structures of Arabidopsis thaliana GDP-D-Mannose Pyrophosphorylase VITAMIN C DEFECTIVE 1. Front Plant Sci, 13, 2022
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7CRC
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![BU of 7crc by Molmil](/molmil-images/mine/7crc) | Cryo-EM structure of plant NLR RPP1 tetramer in complex with ATR1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Avirulence protein ATR1, ... | Authors: | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | Deposit date: | 2020-08-13 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science, 370, 2020
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7C6O
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7CRB
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![BU of 7crb by Molmil](/molmil-images/mine/7crb) | Cryo-EM structure of plant NLR RPP1 LRR-ID domain in complex with ATR1 | Descriptor: | Avirulence protein ATR1, NAD+ hydrolase (NADase) | Authors: | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | Deposit date: | 2020-08-13 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science, 370, 2020
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7CJY
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7DFV
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![BU of 7dfv by Molmil](/molmil-images/mine/7dfv) | Cryo-EM structure of plant NLR RPP1 tetramer core part | Descriptor: | NAD+ hydrolase (NADase) | Authors: | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | Deposit date: | 2020-11-10 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science, 370, 2020
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7EQH
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7F4R
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![BU of 7f4r by Molmil](/molmil-images/mine/7f4r) | Crystal structure of MTA1 | Descriptor: | MT-a70 family protein | Authors: | Chen, J, Liu, L. | Deposit date: | 2021-06-21 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural basis for MTA1c-mediated DNA N6-adenine methylation Nat Commun, 13, 2022
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7EZG
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![BU of 7ezg by Molmil](/molmil-images/mine/7ezg) | The structure of the human METTL6 enzyme in complex with SAH | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA N(3)-methylcytidine methyltransferase METTL6 | Authors: | Xie, W, Chen, R, Zhou, J, Liu, L. | Deposit date: | 2021-06-01 | Release date: | 2022-01-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human METTL6, the m 3 C methyltransferase. Commun Biol, 4, 2021
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7UDW
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![BU of 7udw by Molmil](/molmil-images/mine/7udw) | Designed pentameric proton channel QQLL | Descriptor: | De novo designed pentameric proton channel QQLL | Authors: | Kratochvil, H.T, Thomaston, J.L, Mravic, M, Nicoludis, J, Liu, L, DeGrado, W.F. | Deposit date: | 2022-03-20 | Release date: | 2022-04-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
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7UDV
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7UDZ
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![BU of 7udz by Molmil](/molmil-images/mine/7udz) | Designed pentameric proton channel LQLL | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed pentameric proton channel LQLL | Authors: | Kratochvil, H.T, Thomaston, J.L, Mravic, M, Nicoludis, J.M, Liu, L, DeGrado, W.F. | Deposit date: | 2022-03-20 | Release date: | 2022-04-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
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7UDY
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![BU of 7udy by Molmil](/molmil-images/mine/7udy) | Designed pentameric channel QLLL | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Designed channel QLLL | Authors: | Kratochvil, H.T, Thomaston, J.L, Liu, L, DeGrado, W.F. | Deposit date: | 2022-03-20 | Release date: | 2022-04-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
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7UDX
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![BU of 7udx by Molmil](/molmil-images/mine/7udx) | Designed pentameric proton channel QLQL | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed pentameric proton channel QLQL | Authors: | Kratochvil, H.T, Thomaston, J.L, Liu, L, DeGrado, W.F. | Deposit date: | 2022-03-20 | Release date: | 2022-04-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
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7X1U
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![BU of 7x1u by Molmil](/molmil-images/mine/7x1u) | Structure of Thyrotropin-Releasing Hormone Receptor bound with an Endogenous Peptide Agonist TRH. | Descriptor: | Endogenous Peptide Agonist TRH, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-02-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
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7XAV
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![BU of 7xav by Molmil](/molmil-images/mine/7xav) | Structure of somatostatin receptor 2 bound with lanreotide. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-03-19 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8, 2022
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7XAT
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![BU of 7xat by Molmil](/molmil-images/mine/7xat) | Structure of somatostatin receptor 2 bound with SST14. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-03-19 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8, 2022
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7XAU
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![BU of 7xau by Molmil](/molmil-images/mine/7xau) | Structure of somatostatin receptor 2 bound with octreotide. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-03-19 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8, 2022
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7X1T
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![BU of 7x1t by Molmil](/molmil-images/mine/7x1t) | Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin. | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... | Authors: | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | Deposit date: | 2022-02-24 | Release date: | 2022-08-31 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue. Cell Res., 32, 2022
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2VXK
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![BU of 2vxk by Molmil](/molmil-images/mine/2vxk) | Structural comparison between Aspergillus fumigatus and human GNA1 | Descriptor: | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, COENZYME A, GLUCOSAMINE 6-PHOSPHATE ACETYLTRANSFERASE, ... | Authors: | Hurtado-Guerrero, R, Raimi, O.G, Min, J, Zeng, H, Vallius, L, Shepherd, S, Ibrahim, A.F.M, Wu, H, Plotnikov, A.N, van Aalten, D.M.F. | Deposit date: | 2008-07-05 | Release date: | 2008-07-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Kinetic Differences between Human and Aspergillus Fumigatus D-Glucosamine-6- Phosphate N-Acetyltransferase. Biochem.J., 415, 2008
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7RCL
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![BU of 7rcl by Molmil](/molmil-images/mine/7rcl) | Crystal Structure of ADP-bound Galactokinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ... | Authors: | Whitby, F.G, Hall, M.D. | Deposit date: | 2021-07-07 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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7RCM
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![BU of 7rcm by Molmil](/molmil-images/mine/7rcm) | Crystal Structure of ADP-bound Galactokinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... | Authors: | Whitby, F.G. | Deposit date: | 2021-07-07 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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