7XAU
Structure of somatostatin receptor 2 bound with octreotide.
Summary for 7XAU
Entry DOI | 10.2210/pdb7xau/pdb |
EMDB information | 33099 |
Descriptor | Somatostatin receptor type 2,LargeBit, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | g protein coupled receptor, cryo-em, sst analogues, polypeptide drugs, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 184373.95 |
Authors | Bo, Q.,Yang, F.,Li, Y.G.,Meng, X.Y.,Zhang, H.H.,Zhou, Y.X.,Ling, S.L.,Sun, D.M.,Lv, P.,Liu, L.,Shi, P.,Tian, C.L. (deposition date: 2022-03-19, release date: 2022-08-31) |
Primary citation | Bo, Q.,Yang, F.,Li, Y.,Meng, X.,Zhang, H.,Zhou, Y.,Ling, S.,Sun, D.,Lv, P.,Liu, L.,Shi, P.,Tian, C. Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues. Cell Discov, 8:47-47, 2022 Cited by PubMed: 35595746DOI: 10.1038/s41421-022-00405-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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